Ten principles of heterochromatin formation and function
RC Allshire, HD Madhani - Nature reviews Molecular cell biology, 2018 - nature.com
Heterochromatin is a key architectural feature of eukaryotic chromosomes, which endows
particular genomic domains with specific functional properties. The capacity of …
particular genomic domains with specific functional properties. The capacity of …
RNA-mediated epigenetic regulation of gene expression
D Holoch, D Moazed - Nature Reviews Genetics, 2015 - nature.com
Diverse classes of RNA, ranging from small to long non-coding RNAs, have emerged as key
regulators of gene expression, genome stability and defence against foreign genetic …
regulators of gene expression, genome stability and defence against foreign genetic …
Epigenetic inheritance uncoupled from sequence-specific recruitment
K Ragunathan, G Jih, D Moazed - Science, 2015 - science.org
INTRODUCTION Changes in histone posttranslational modifications are associated with
epigenetic states that define distinct patterns of gene expression. Whereas sequence …
epigenetic states that define distinct patterns of gene expression. Whereas sequence …
Small RNAs in the transgenerational inheritance of epigenetic information
L Duempelmann, M Skribbe, M Bühler - Trends in Genetics, 2020 - cell.com
In recent years it has become evident that RNA interference-related mechanisms can
mediate the deposition and transgenerational inheritance of specific chromatin modifications …
mediate the deposition and transgenerational inheritance of specific chromatin modifications …
Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription
G Jih, N Iglesias, MA Currie, NV Bhanu, JA Paulo… - Nature, 2017 - nature.com
Heterochromatic DNA domains have important roles in the regulation of gene expression
and maintenance of genome stability by silencing repetitive DNA elements and transposons …
and maintenance of genome stability by silencing repetitive DNA elements and transposons …
Epigenetic inheritance mediated by coupling of RNAi and histone H3K9 methylation
R Yu, X Wang, D Moazed - Nature, 2018 - nature.com
Histone post-translational modifications (PTMs) are associated with epigenetic states that
form the basis for cell-type-specific gene expression,. Once established, histone PTMs can …
form the basis for cell-type-specific gene expression,. Once established, histone PTMs can …
An essential role for the piRNA pathway in regulating the ribosomal RNA pool in C. elegans
L Wahba, L Hansen, AZ Fire - Developmental cell, 2021 - cell.com
Piwi-interacting RNAs (piRNAs) are RNA effectors with key roles in maintaining genome
integrity and promoting fertility in metazoans. In Caenorhabditis elegans loss of piRNAs …
integrity and promoting fertility in metazoans. In Caenorhabditis elegans loss of piRNAs …
Dicer promotes transcription termination at sites of replication stress to maintain genome stability
Nuclear RNAi is an important regulator of transcription and epigenetic modification, but the
underlying mechanisms remain elusive. Using a genome-wide approach in the fission yeast …
underlying mechanisms remain elusive. Using a genome-wide approach in the fission yeast …
The Paf1 complex represses small-RNA-mediated epigenetic gene silencing
KM Kowalik, Y Shimada, V Flury, MB Stadler, J Batki… - Nature, 2015 - nature.com
RNA interference (RNAi) refers to the ability of exogenously introduced double-stranded
RNA to silence expression of homologous sequences. Silencing is initiated when the …
RNA to silence expression of homologous sequences. Silencing is initiated when the …
Non-coding RNAs and transposable elements in plant genomes: emergence, regulatory mechanisms and roles in plant development and stress responses
J Hou, D Lu, AS Mason, B Li, M Xiao, S An, D Fu - Planta, 2019 - Springer
Main conclusion This review will provide evidence for the indispensable function of these
elements in regulating plant development and resistance to biotic and abiotic stresses, as …
elements in regulating plant development and resistance to biotic and abiotic stresses, as …