Adenosine kinase (ADK; EC 2.7. 1.20) is an evolutionarily conserved phosphotransferase
that converts the purine ribonucleoside adenosine into 5′-adenosine-monophosphate …

Intra-and extracellular adenosine levels rise in response to physiological stimuli and with
metabolic/energetic perturbations, inflammatory challenge and tissue injury. Extracellular …

Adenosine is a nucleoside that impacts the cardiovascular system via the activation of its
membrane receptors, named A1R, A2AR, A2BR and A3R. Adenosine is released during …

Traditionally, the single most unique feature of the immune system has been attributed to its
capability to discriminate between self (eg, host proteins) and nonself (eg, pathogens). More …

Adenosine is an endogenous nucleoside that plays a major role in the physiology and
physiopathology of the coronary artery system, mainly by activating its A2A receptors …

Background. Activation of the adenosine A2B receptor (A2BR) can reduce myocardial
ischemia/reperfusion (IR) injury. However, the mechanism underlying the A2BR‐mediated …

Significance: Acute myocardial infarction (AMI) is a leading cause of death worldwide. Post-
AMI survival rates have increased with the introduction of angioplasty as a primary coronary …

Adenosine is an endogenous nucleoside which strongly impacts the cardiovascular system.
Adenosine is released mostly by endothelial cells and myocytes during ischemia or hypoxia …

Complex regional pain syndrome type I (CRPS-I) is a chronic painful condition. We
investigated whether manual therapy (MT), in a chronic post-ischemia pain (CPIP) model, is …

Acute pulmonary inflammation is still a frightening complication in intensive care units. In our
previous study, we determined that heme oxygenase (HO)-1 had anti-inflammatory effects in …