Engineering nanosystems to overcome barriers to cancer diagnosis and treatment

SO Alhaj-Suliman, EI Wafa, AK Salem - Advanced drug delivery reviews, 2022 - Elsevier
Over the past two decades, multidisciplinary investigations into the development of
nanoparticles for medical applications have continually increased. However, nanoparticles …

Cationic nanoparticles enhance T cell tumor infiltration and antitumor immune responses to a melanoma vaccine

R Smith, EI Wafa, SM Geary, K Ebeid… - Science …, 2022 - science.org
In clinical settings, cancer vaccines as monotherapies have displayed limited success
compared to other cancer immunotherapeutic treatments. Nanoscale formulations have the …

Pentaerythritol-based lipid A bolsters the antitumor efficacy of a polyanhydride particle-based cancer vaccine

EI Wafa, SM Geary, KA Ross, JT Goodman… - … , Biology and Medicine, 2019 - Elsevier
The primary objective of this study was to enhance the antitumor efficacy of a model cancer
vaccine through co-delivery of pentaerythritol lipid A (PELA), an immunological adjuvant …

Poly (diaminosulfide) microparticle-based vaccine for delivery of leptospiral antigens

EI Wafa, JH Wilson-Welder, RL Hornsby… - …, 2020 - ACS Publications
Leptospirosis is a debilitating infectious disease that detrimentally affects both animals and
humans; therefore, disease prevention has become a high priority to avoid high incidence …

Poly (diaminosulfide) particle-based vaccine

AK Salem, EI Wafa, SM Geary, NB Bowden… - US Patent …, 2024 - Google Patents
US11904006B2 - Poly(diaminosulfide) particle-based vaccine - Google Patents US11904006B2
- Poly(diaminosulfide) particle-based vaccine - Google Patents Poly(diaminosulfide) …