Patients with obesity have a high prevalence of nonalcoholic fatty liver disease (NAFLD),
representing a spectrum of simple steatosis to nonalcoholic steatohepatitis (NASH), without …

Growth hormone (GH) is critical for achieving normal structural growth. In addition, GH plays
an important role in regulating metabolic function. GH acts through its GH receptor (GHR) to …

Growth hormone (GH) is secreted by the anterior pituitary gland and plays a key role in
controlling tissue and body growth. While basal GH secretion is considerably reduced along …

Growth hormone (GH) is secreted by somatotropic cells of the anterior pituitary gland. The
classical effects of GH comprise the stimulation of cell proliferation, tissue and body growth …

Growth hormone (GH) secretion is controlled by short and long negative feedback loops. In
this regard, both GH (short-loop feedback) and insulin-like growth factor 1 (IGF-1; long-loop …

Growth hormone (GH) acts in several hypothalamic neuronal populations to modulate
metabolism and the autoregulation of GH secretion via negative-feedback loops. However …

Growth hormone (GH) receptor (GHR) is abundantly expressed in neurons that co‐release
the agouti‐related protein (AgRP) and neuropeptide Y (NPY) in the arcuate nucleus of the …

Agouti-related protein (AgRP) is a neuropeptide synthesized by AgRP/NPY neurons and
transcribed as 132 amino acids in humans and 142 amino acids (AgRP1) in Japanese …

Evidence for hypothalamic regulation of energy homeostasis and thermoregulation in brown
adipose tissue (BAT) during aging has been well recognized, yet the central molecular …

Corticotropin-releasing hormone (CRH) cells are the dominant neuronal population
responsive to the growth hormone (GH) in the paraventricular nucleus of the hypothalamus …