Non-motor features of Parkinson disease
AHV Schapira, KR Chaudhuri, P Jenner - Nature Reviews …, 2017 - nature.com
Many of the motor symptoms of Parkinson disease (PD) can be preceded, sometimes for
several years, by non-motor symptoms that include hyposmia, sleep disorders, depression …
several years, by non-motor symptoms that include hyposmia, sleep disorders, depression …
Pathophysiology of motor dysfunction in Parkinson's disease as the rationale for drug treatment and rehabilitation
F Magrinelli, A Picelli, P Tocco, A Federico… - Parkinson's …, 2016 - Wiley Online Library
Cardinal motor features of Parkinson's disease (PD) include bradykinesia, rest tremor, and
rigidity, which appear in the early stages of the disease and largely depend on …
rigidity, which appear in the early stages of the disease and largely depend on …
Pain modulates dopamine neurons via a spinal–parabrachial–mesencephalic circuit
Pain decreases the activity of many ventral tegmental area (VTA) dopamine (DA) neurons,
yet the underlying neural circuitry connecting nociception and the DA system is not …
yet the underlying neural circuitry connecting nociception and the DA system is not …
Non-motor symptoms of Parkinson's disease: dopaminergic pathophysiology and treatment
KR Chaudhuri, AHV Schapira - The Lancet Neurology, 2009 - thelancet.com
Several studies, including work from the Parkinson's disease (PD) non-motor group and
others, have established that the non-motor symptoms of PD are common, occur across all …
others, have established that the non-motor symptoms of PD are common, occur across all …
Evidence for early and regular physical therapy and exercise in Parkinson's disease
TD Ellis, C Colón-Semenza, TR DeAngelis… - Seminars in …, 2021 - thieme-connect.com
Advances in medical management of Parkinson's disease (PD) have resulted in living
longer with disability. Although disability worsens over the course of the disease, there are …
longer with disability. Although disability worsens over the course of the disease, there are …
Sensory aspects of movement disorders
N Patel, J Jankovic, M Hallett - The Lancet Neurology, 2014 - thelancet.com
Movement disorders, which include disorders such as Parkinson's disease, dystonia,
Tourette's syndrome, restless legs syndrome, and akathisia, have traditionally been …
Tourette's syndrome, restless legs syndrome, and akathisia, have traditionally been …
[HTML][HTML] Reward deficiency and anti-reward in pain chronification
D Borsook, C Linnman, V Faria, AM Strassman… - Neuroscience & …, 2016 - Elsevier
Converging lines of evidence suggest that the pathophysiology of pain is mediated to a
substantial degree via allostatic neuroadaptations in reward-and stress-related brain …
substantial degree via allostatic neuroadaptations in reward-and stress-related brain …
Pathophysiology of somatosensory abnormalities in Parkinson disease
A Conte, N Khan, G Defazio, JC Rothwell… - Nature Reviews …, 2013 - nature.com
Abstract Changes in sensory function that have been described in patients with Parkinson
disease (PD) can be either'pure'disorders of conscious perception such as elevations in …
disease (PD) can be either'pure'disorders of conscious perception such as elevations in …
Neuropathobiology of non-motor symptoms in Parkinson disease
KA Jellinger - Journal of neural transmission, 2015 - Springer
Parkinson disease (PD) is a multisystem disorder associated with α-synuclein aggregates
throughout the central, autonomic, and peripheral nervous system, clinically characterized …
throughout the central, autonomic, and peripheral nervous system, clinically characterized …
Gender-related differences in the burden of non-motor symptoms in Parkinson's disease
P Martinez-Martin, C Falup Pecurariu, P Odin… - Journal of …, 2012 - Springer
Differences in the expression of non-motor symptoms (NMS) by Parkinson's disease (PD)
patients may have important implications for their management and prognosis. Gender is a …
patients may have important implications for their management and prognosis. Gender is a …