Extracting organic compounds from plants and developing derivatives are essential
methods for drug discovery. Diosgenin, extracted from Dioscoreaceae plants, is a type of …

There is great interest in developing chemical technologies to achieve regioselective and
stereoselective reactions since only one enantiomer is required for producing the chiral …

Although the discovery of antibiotics has decreased the spread and severity of infectious
diseases, their uncontrolled use has lead to the emergence of bacterial resistance to …

Biotransformation of neoruscogenin (NR, 1, spirosta-5, 25 (27)-diene-1β, 3β-diol), the major
bioactive sapogenin of Ruscus preparations, was carried out with the endophytic fungus …

Microbial-catalyzed biotransformations have considerable potential for the generation of an
enormous variety of structurally diversified organic compounds, especially natural products …

Microbial transformation of diosgenin (3β-hydroxy-5-spirostene) using white-rot fungus
Coriolus versicolor afforded four previously unreported polyhydroxylated steroids, 25 (R) …

This study explores the bioconversion of diosgenin by Yarrowia lipolytica P01a, focusing on
enhancing the antioxidant, antifungal, and herbicidal activities of the resulting extracts. The …

Biotransformation of a steroidal contraceptive drug, etonogestrel (1),(13-ethyl-17β-hydroxy-
11-methylene-18, 19-dinor-17α-pregn-4-en-20-yn-3-one) was investigated with …

Microbial transformation of oxandrolone (1) was carried out by using Cunninghamella
blakesleeana and Macrophomina phaseolina. Biotransformation of 1 with M. phaseolina …

Microbial transformation of diosgenin ((25R)-spirost-5-en-3β-ol) using Cunninghamella
blakesleana AS 3.970, afforded eleven polyhydroxylated derivatives, including seven …