NSAIDs in CKD: are they safe?

M Baker, MA Perazella - American Journal of Kidney Diseases, 2020 - Elsevier
The management of pain in patients with chronic kidney disease (CKD) is challenging for
many reasons. These patients have increased susceptibility to adverse drug effects due to …

[HTML][HTML] Drug-induced nephrotoxicity

GTM Sales, RD Foresto - Revista da Associação Médica Brasileira, 2020 - SciELO Brasil
Acute kidney injury is a very common diagnosis, present in up to 60% of critical patients, and
its third main cause is drug toxicity. Nephrotoxicity can be defined as any renal injury caused …

Management of osteoarthritis: expert opinion on NSAIDs

A Magni, P Agostoni, C Bonezzi, G Massazza, P Menè… - Pain and therapy, 2021 - Springer
Osteoarthritis (OA) is a leading cause of disability among older adults worldwide. Treatment
aims are to alleviate inflammatory pain and improve physical function through non …

Kidney damage from nonsteroidal anti‐inflammatory drugs—Myth or truth? Review of selected literature

S Drożdżal, K Lechowicz, B Szostak… - Pharmacology …, 2021 - Wiley Online Library
Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely available drugs with anti‐
inflammatory and analgesic properties. Their mechanism of action is associated with the …

Acute kidney injury associated with non-steroidal anti-inflammatory drugs

N Klomjit, P Ungprasert - European journal of internal medicine, 2022 - Elsevier
Non-steroidal anti-inflammatory drugs (NSAIDs) are ones of the commonly prescribed drugs
worldwide. They primarily inhibit cyclooxygenase (COX) enzyme which is responsible for …

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Usage and co-prescription with other potentially interacting drugs in elderly: A cross-sectional study

N Abdu, A Mosazghi, S Teweldemedhin, L Asfaha… - PloS one, 2020 - journals.plos.org
Globally, usage of non-steroidal anti-inflammatory drugs (NSAIDs) in elderly with chronic
pain has been reported as frequent. Though NSAIDs are fundamental in maintaining their …

[HTML][HTML] Proprotein convertase subtilisin/kexin type 6 (PCSK6) is a likely antigenic target in membranous nephropathy and nonsteroidal anti-inflammatory drug use

S Sethi, MC Moura, B Madden, H Debiec, SH Nasr… - Kidney international, 2023 - Elsevier
Drugs are an important secondary cause of membranous nephropathy (MN) with the most
common drugs associated with MN being nonsteroidal anti-inflammatory drugs (NSAIDs) …

The immune system and idiopathic nephrotic syndrome

RE Campbell, JM Thurman - … Journal of the American Society of …, 2022 - journals.lww.com
Idiopathic nephrotic syndrome often responds to immunosuppressive treatment.
Nevertheless, this syndrome—and the drugs used to treat it—remain important causes of …

NSAIDs and nephrotic syndrome

E Mérida, M Praga - Clinical Journal of the American Society of …, 2019 - journals.lww.com
The association between nonsteroidal anti-inflammatory drugs (NSAIDs) and nephrotic
syndrome has long been recognized. Minimal change disease and membranous …

Quality of care after AKI development in the hospital: consensus from the 22nd Acute Disease Quality Initiative (ADQI) conference

E Macedo, A Bihorac, ED Siew, PM Palevsky… - European journal of …, 2020 - Elsevier
Background Acute kidney injury (AKI) is independently associated with increased morbidity
and mortality. Quality improvement has been identified as an important goal in the care of …