Co-delivery of drugs and plasmid DNA for cancer therapy

PY Teo, W Cheng, JL Hedrick, YY Yang - Advanced drug delivery reviews, 2016 - Elsevier
Cancer is an extremely complex disease involving multiple signaling pathways that enable
tumor cells to evade programmed cell death, thus making cancer treatment extremely …

Nanomedicines for the treatment of hematological malignancies

AK Deshantri, AV Moreira, V Ecker… - Journal of controlled …, 2018 - Elsevier
Hematological malignancies (HM) are a collection of malignant transformations originating
from cells in the primary or secondary lymphoid organs. Leukemia, lymphoma, and multiple …

[HTML][HTML] A light-driven dual-nanotransformer with deep tumor penetration for efficient chemo-immunotherapy

J Peng, F Chen, Y Liu, F Zhang, L Cao, Q You… - Theranostics, 2022 - ncbi.nlm.nih.gov
Designing a transformable nanosystem with improved tumor accumulation and penetration
by tuning multiple physicochemical properties remains a challenge. Here, a near-infrared …

Design of nanocarriers based on complex biological barriers in vivo for tumor therapy

J Liu, M Li, Z Luo, L Dai, X Guo, K Cai - Nano Today, 2017 - Elsevier
Nanoscale drug delivery systems (NDDS) have shown great potential in tumor treatment
due to its unique advantages, especially its unique enhanced permeability and retention …

Cell surface Nucleolin represents a novel cellular target for neuroblastoma therapy

C Brignole, V Bensa, NA Fonseca, G Del Zotto… - Journal of Experimental …, 2021 - Springer
Background Neuroblastoma (NB) represents the most frequent and aggressive form of
extracranial solid tumor of infants. Nucleolin (NCL) is a protein overexpressed and partially …

Preparation and characterization of stable nanoliposomal formulations of curcumin with high loading efficacy: in vitro and in vivo anti-tumor study

M Karimi, F Gheybi, P Zamani, M Mashreghi… - International journal of …, 2020 - Elsevier
Liposomal formulations were made using Solvent-assisted active loading technology
(SALT). Two formulations composed of HSPC: DPPG: Chol: DSPE-mPEG 2000 (PG …

Progress on the application of bortezomib and bortezomib-based nanoformulations

J Liu, R Zhao, X Jiang, Z Li, B Zhang - Biomolecules, 2021 - mdpi.com
Bortezomib (BTZ) is the first proteasome inhibitor approved by the Food and Drug
Administration. It can bind to the amino acid residues of the 26S proteasome, thereby …

Assembly of catechol-modified polymer brushes for drug delivery

K Zhao, Z Gao, D Song, P Zhang, J Cui - Polymer Chemistry, 2022 - pubs.rsc.org
Therapeutic nanoparticles (NPs) have shown their potential for biomedical applications (eg,
drug delivery). In this study, we report the synthesis of a bottlebrush block copolymer by ring …

Enhanced anticancer efficacy of paclitaxel through multistage tumor-targeting liposomes modified with RGD and KLA peptides

J Sun, L Jiang, Y Lin, EM Gerhard, X Jiang… - International journal …, 2017 - Taylor & Francis
Mitochondria serve as both “energy factories” and “suicide weapon stores” of cells. Targeted
delivery of cytotoxic drugs to the mitochondria of tumor cells and tumor vascular cells is a …

Development of highly efficient nanocarrier-mediated delivery approaches for cancer therapy

K Jeong, CS Kang, Y Kim, YD Lee, IC Kwon, S Kim - Cancer letters, 2016 - Elsevier
Nanocarriers (NCs) are a group of nano-sized vehicles devised to deliver drugs to targeted
malignant tissues or organs that provide remarkably improved targeting efficiency and …