In accordance with their common but also divergent physiological actions, human urotensin
II (1) and urotensin II-related peptide (2) could stabilize specific urotensin II receptor (UTR) …

The urotensinergic system, formed by a G protein‐coupled receptor (GPCR) termed UT and
two endogenous peptide ligands Urotensin II (UII, H‐Glu‐Thr‐Pro‐Asp‐[Cys‐Phe‐Trp‐Lys …

A proof-of-concept library of pyrrolodiazepinone small molecules was designed based on
the Bip-Lys-Tyr motif found in a recently described modulator of the urotensinergic system …

We have optimized 1 (P5U) and urantide, two important ligands at the h-UT receptor,
designing several analogues by the exchange of the Tyr9 residue with different unnatural …

The urotensin II receptor (UTR) has long been studied mainly for its involvement in the
cardiovascular homeostasis both in health and disease state. Two endogenous ligands …

A Lewis acid-catalysed diastereoselective [4+ 2] cycloaddition of vinylindoles and methyl 2-
acetamidoacrylate, leading to methyl 3-acetamido-1, 2, 3, 4-tetrahydrocarbazole-3 …

The urotensinergic system, involved in the development and/or progression of numerous
pathological conditions, is composed of one G protein-coupled receptor (UT) and two …

Urotensin II (U‐II) is a disulfide bridged peptide hormone identified as the ligand of a G
protein‐coupled receptor. Human U‐II (H‐Glu‐Thr‐Pro‐Asp‐c [Cys‐Phe‐Trp‐Lys‐Tyr‐Cys] …

Urotensin II (UII) and its paralog peptide, urotensin II-related peptide (URP), exert not only
common but also divergent actions through the activation of UT, a specific membrane-bound …

While sharing common biological activity, the two endogenous ligands of the G protein-
coupled receptor UT, eg urotensin II (UII) and urotensin II-related peptide (URP), also exhibit …