Different Schiff bases—structure, importance and classification

E Raczuk, B Dmochowska, J Samaszko-Fiertek… - Molecules, 2022 - mdpi.com
Schiff bases are a vast group of compounds characterized by the presence of a double bond
linking carbon and nitrogen atoms, the versatility of which is generated in the many ways to …

Biological activities of hydrazone derivatives

S Rollas, Ş Güniz Küçükgüzel - Molecules, 2007 - mdpi.com
There has been considerable interest in the development of novel compounds with
anticonvulsant, antidepressant, analgesic, antiinflammatory, antiplatelet, anti-malarial …

Spectroscopic studies, antimicrobial activity, and computational investigations of hydrazone ligands endowed metal chelates

T Arora, J Devi, A Dubey, A Tufail… - Applied Organometallic …, 2023 - Wiley Online Library
Our current efforts are aimed to synthesize 16 complexes of Co (II), Ni (II), Cu (II), and Zn (II)
metal ions from heterocyclic hydrazone ligands by condensation reaction of 2, 6 …

Mini-review of the importance of hydrazides and their derivatives—Synthesis and biological activity

SN Mali, BR Thorat, DR Gupta, A Pandey - Engineering proceedings, 2021 - mdpi.com
Organic acid hydrazides include a vast group of organic derivatives of hydrazines containing
the active functional group (-C (= O) NHNH2). Acid hydrazones were important bidentate …

Repositioning of acefylline as anti-cancer drug: Synthesis, anticancer and computational studies of azomethines derived from acefylline tethered 4-amino-3-mercapto …

I Shahzadi, AF Zahoor, B Tüzün, A Mansha, MN Anjum… - Plos one, 2022 - journals.plos.org
Novel azomethines derived from acefylline tethered triazole hybrids (7a-k) have been
synthesized and evaluated against human liver cancer cell line (Hep G2) using MTT assay …

A review on biological activities and chemical synthesis of hydrazide derivatives

R Narang, B Narasimhan… - Current medicinal …, 2012 - ingentaconnect.com
There has been considerable interest in the development of novel compounds with
anticonvulsant, antioxidant, hormone antagonist, analgesic, anti-inflammatory, antiplatelet …

Design, synthesis and evaluation of antiinflammatory, analgesic and ulcerogenicity studies of novel S-substituted phenacyl-1, 3, 4-oxadiazole-2-thiol and Schiff bases …

SV Bhandari, KG Bothara, MK Raut, AA Patil… - Bioorganic & medicinal …, 2008 - Elsevier
Diclofenac sodium is being used for its anti-inflammatory actions since 28 years, but as all
the NSAIDs are suffering from the deadlier GI toxicities, diclofenac sodium is also not an …

Synthesis and structure–activity relationships of novel 1-arylmethyl-3-aryl-1H-pyrazole-5-carbohydrazide hydrazone derivatives as potential agents against A549 lung …

Y Xia, CD Fan, BX Zhao, J Zhao, DS Shin… - European journal of …, 2008 - Elsevier
A series of novel 1-arylmethyl-3-aryl-1H-pyrazole-5-carbohydrazide hydrazone derivatives
were synthesized and the effects of all the compounds on A549 cell growth were …

Preparation and drug delivery of dextran-drug complex

S Huang, G Huang - Drug delivery, 2019 - Taylor & Francis
Dextran as a drug carrier for inhibiting cancer cells effectively reduces the toxic and side
effects of the drug in the biological body. Targeting improves the concentration of active …

Synthesis of novel substituted pyrazole-5-carbohydrazide hydrazone derivatives and discovery of a potent apoptosis inducer in A549 lung cancer cells

LW Zheng, LL Wu, BX Zhao, WL Dong… - Bioorganic & medicinal …, 2009 - Elsevier
A series of novel 3-aryl-1-(4-tert-butylbenzyl)-1H-pyrazole-5-carbohydrazide hydrazone
derivatives were synthesized and the effects of all the compounds on A549 cell growth were …