Imaging the dynamics and interactions of biomolecules at the single-molecule level in live
cells and reconstituted systems has generated unprecedented knowledge about the …

Biological membranes are complex, heterogeneous, and dynamic systems that play roles in
the compartmentalization and protection of cells from the environment. It is still a challenge …

Optical microscopy has undergone significant changes in recent decades due to the
improved diffraction limit of optical resolution and the development of high-resolution …

The conserved Wnt signaling has been classified as two categories of canonical and
noncanonical Wnt signaling. With a high promiscuity of Wnt signaling, how receptors from …

Single-particle tracking (SPT) has become a powerful tool to monitor the dynamics of
membrane proteins in living cells. However, permanent labeling strategies for SPT suffer …

Terminally misfolded or otherwise damaged proteins of the Endoplasmic Reticulum (ER) are
degraded by the proteasome in a process termed Endoplasmic Reticulum Associated …