Polymer scaffolds as drug delivery systems

IR Calori, G Braga, PCC de Jesus, H Bi… - European Polymer …, 2020 - Elsevier
Drug delivery scaffolds are smart alternatives to conventional formulations and allow for
controlled spatiotemporal releases of active compounds. In several fields of human health …

Shaping of hepatic ischemia/reperfusion events: the crucial role of mitochondria

JS Teodoro, RT Da Silva, IF Machado… - Cells, 2022 - mdpi.com
Hepatic ischemia reperfusion injury (HIRI) is a major hurdle in many clinical scenarios,
including liver resection and transplantation. Various studies and countless surgical events …

Scaffolds based on alginate-PEG methyl ether methacrylate-Moringa oleifera-Aloe vera for wound healing applications

I Rubio-Elizalde, J Bernáldez-Sarabia… - Carbohydrate …, 2019 - Elsevier
This study sought to improve the handling, stability to aqueous medium and healing
properties of alginate-based three-dimensional structures to be applied as wound scaffolds …

A rechargeable drug delivery system based on pNIPAM hydrogel for the local release of curcumin

Z Ayar, M Shafieian, N Mahmoodi… - Journal of Applied …, 2021 - Wiley Online Library
This study was designed to develop a drug delivery system based on poly (N‐
isopropylacrylamide)(pNIPAM) hydrogel and a suitable solvent to enhance solubility and …

Radical Scavenging, Hemocompatibility, and Antibacterial Activity against MDR Acinetobacter baumannii in Alginate-Based Aerogels Containing Lipoic Acid-Capped …

KD Martínez-García, T Zertuche-Arias… - ACS …, 2024 - ACS Publications
Retaining the hemocompatibility, supporting cell growth, and exhibiting anti-inflammatory
and antioxidant properties, while having antimicrobial activity, particularly against multidrug …

Therapeutic interventions in sepsis: current and anticipated pharmacological agents

P Shukla, GM Rao, G Pandey, S Sharma… - British journal of …, 2014 - Wiley Online Library
Sepsis is a clinical syndrome characterized by a multisystem response to a pathogenic
assault due to underlying infection that involves a combination of interconnected …

Polymeric materials for immune engineering: Molecular interaction to biomaterial design

SS Soni, CB Rodell - Acta biomaterialia, 2021 - Elsevier
Biomaterials continue to evolve as complex engineered tools for interactively instructing
biological systems, aiding in the understanding and treatment of various disease states …

[HTML][HTML] Convergence of nanomedicine and neutrophils for drug delivery

S Yuan, Q Hu - Bioactive Materials, 2024 - Elsevier
Neutrophils have recently emerged as promising carriers for drug delivery due to their
unique properties including rapid response toward inflammation, chemotaxis, and …

[HTML][HTML] Engineering LNPs with polysarcosine lipids for mRNA delivery

DD Kang, X Hou, L Wang, Y Xue, H Li, Y Zhong… - Bioactive Materials, 2024 - Elsevier
Since the approval of the lipid nanoparticles (LNP)-mRNA vaccines against the SARS-CoV-
2 virus, there has been an increased interest in the delivery of mRNA through LNPs …

Gold nanoparticle and polyethylene glycol in neural regeneration in the treatment of neurodegenerative diseases

T Aghaie, MH Jazayeri, M Manian… - Journal of Cellular …, 2019 - Wiley Online Library
Gold nanoparticles (GNs) have unique characteristics, for example, stability,
biocompatibility, small dimensions, and low toxicity. Several clinical applications have been …