Genetics of diabetes mellitus and diabetes complications
Diabetes is one of the fastest growing diseases worldwide, projected to affect 693 million
adults by 2045. Devastating macrovascular complications (cardiovascular disease) and …
adults by 2045. Devastating macrovascular complications (cardiovascular disease) and …
[HTML][HTML] From pre-diabetes to diabetes: diagnosis, treatments and translational research
Diabetes, a silent killer, is one of the most widely prevalent conditions of the present time.
According to the 2017 International Diabetes Federation (IDF) statistics, the global …
According to the 2017 International Diabetes Federation (IDF) statistics, the global …
Genetic markers of type 2 diabetes: Progress in genome‐wide association studies and clinical application for risk prediction: 2 型糖尿病的遗传标记: 风险预测的全 …
X Wang, G Strizich, Y Hu, T Wang… - Journal of …, 2016 - Wiley Online Library
摘要2 型糖尿病已经成为全球公共卫生的主要挑战. 迄今为止, 通过全基因组关联研究(genome‐
wide association studies, GWAS) 总共已经鉴定出了83 个2 型糖尿病易感位点. 为了发现2 …
wide association studies, GWAS) 总共已经鉴定出了83 个2 型糖尿病易感位点. 为了发现2 …
A comprehensive overview on osteoporosis and its risk factors
F Pouresmaeili, B Kamalidehghan… - … and clinical risk …, 2018 - Taylor & Francis
Osteoporosis is a bone disorder with remarkable changes in bone biologic material and
consequent bone structural distraction, affecting millions of people around the world from …
consequent bone structural distraction, affecting millions of people around the world from …
PPARs in obesity-induced T2DM, dyslipidaemia and NAFLD
Obesity is a worldwide epidemic that predisposes individuals to cardiometabolic
complications, such as type 2 diabetes mellitus (T2DM) and nonalcoholic fatty liver disease …
complications, such as type 2 diabetes mellitus (T2DM) and nonalcoholic fatty liver disease …
[HTML][HTML] Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes
Abstract Type 2 diabetes (T2D) is a very common disease in humans. Here we conduct a
meta-analysis of genome-wide association studies (GWAS) with~ 16 million genetic variants …
meta-analysis of genome-wide association studies (GWAS) with~ 16 million genetic variants …
[HTML][HTML] Chapter 11: Genome-wide association studies
Genome-wide association studies (GWAS) have evolved over the last ten years into a
powerful tool for investigating the genetic architecture of human disease. In this work, we …
powerful tool for investigating the genetic architecture of human disease. In this work, we …
A machine learning-based framework to identify type 2 diabetes through electronic health records
Objective To discover diverse genotype-phenotype associations affiliated with Type 2
Diabetes Mellitus (T2DM) via genome-wide association study (GWAS) and phenome-wide …
Diabetes Mellitus (T2DM) via genome-wide association study (GWAS) and phenome-wide …
[HTML][HTML] Prevention of diabetes and cardiovascular disease in obesity
L La Sala, AE Pontiroli - International journal of molecular sciences, 2020 - mdpi.com
Obesity is one of the major risk factors for the development of both impaired glucose
tolerance (IGT, or prediabetes) and type 2 diabetes (T2D), and its prevalence worldwide …
tolerance (IGT, or prediabetes) and type 2 diabetes (T2D), and its prevalence worldwide …
[HTML][HTML] Genetics of insulin resistance and the metabolic syndrome
AE Brown, M Walker - Current cardiology reports, 2016 - Springer
Insulin resistance and the metabolic syndrome are complex metabolic traits and key risk
factors for the development of cardiovascular disease. They result from the interplay of …
factors for the development of cardiovascular disease. They result from the interplay of …