Urticaria is an inflammatory skin disorder that affects up to 20% of the world population at
some point during their life. It presents with wheals, angioedema or both due to activation …

Novel therapies such as type 2 targeting biologics are emerging treatment options for
patients with chronic inflammatory respiratory diseases, fulfilling the needs of severely …

Chronic spontaneous urticaria (CSU) is a debilitating skin disease characterized by
intensely itchy wheals, angioedema, or both. Symptoms recur spontaneously, on a near …

Urticaria (hives) is a highly prevalent skin disorder that can occur with or without associated
angioedema. Chronic spontaneous urticaria (CSU) is a condition which persists for more …

Guidelines for the treatment of chronic spontaneous urticaria (CSU) recommend the use of
the IgE-targeted biologic omalizumab in patients with antihistamine-refractory disease. The …

Urticaria is a common, mast cell-driven disease presenting with wheals or angioedema or
both. In the last years, urticaria has increasingly attracted notice to clinicians and …

Chronic urticaria is defined as the presence of urticaria for a period exceeding 6 weeks,
assuming symptoms for most days of the week. It is divided into chronic inducible urticarias …

This systematic review evaluates the efficacy and safety of omalizumab for chronic
spontaneous urticaria (CSU). PubMed, Embase, and Cochrane Library were searched for …

Immunoglobulin E (IgE) plays an essential role in many allergic diseases. This review
highlights the role of IgE in atopic dermatitis (AD), a common, chronic, and complex skin …

Basophils are the rarest granulocytes and have long been overlooked in immunological
research due to their rarity and similarities with tissue-resident mast cells. In the last two …