Retinal pigment epithelium-immune system interactions: cytokine production and cytokine-induced changes

GM Holtkamp, A Kijlstra, R Peek, AF De Vos - Progress in retinal and eye …, 2001 - Elsevier
Vision is dependent on proper function of several intraocular structures. Immune responses
to eliminate invading pathogens from the eye may threat vision by causing damage to these …

Role of the retinal vascular endothelial cell in ocular disease

AS Bharadwaj, B Appukuttan, PA Wilmarth… - Progress in retinal and …, 2013 - Elsevier
Retinal endothelial cells line the arborizing microvasculature that supplies and drains the
neural retina. The anatomical and physiological characteristics of these endothelial cells are …

Upregulation of intercellular adhesion molecule-1 (ICAM-1) expression in primary cultures of human brain microvessel endothelial cells by cytokines and …

D Wong, K Dorovini-Zis - Journal of neuroimmunology, 1992 - Elsevier
The expression of intercellular adhesion molecule-1 (ICAM-1) by human cerebral
endothelium was studied in primary cultures of human brain microvessel endothelial cells …

Proliferative vitreoretinopathy: pathobiology, surgical management, and adjunctive treatment.

DG Charteris - The British journal of ophthalmology, 1995 - ncbi.nlm.nih.gov
Surgical repair of rhegmatogenous retinal detachment is currently successful in over 90% of
cases.'-4 Where there is a final failure to reattach the retina this is due to the development of …

Mechanisms of leukocyte migration across the blood–retina barrier

IJ Crane, J Liversidge - Seminars in immunopathology, 2008 - Springer
Immune-mediated inflammation in the retina is regulated by a combination of anatomical,
physiological and immuno-regulatory mechanisms, referred to as the blood–retina barrier …

Ocular immune privilege and retinal pigment epithelial cells

Y Du, B Yan - Journal of Leukocyte Biology, 2023 - academic.oup.com
The ocular tissue microenvironment is immune-privileged and uses multiple
immunosuppressive mechanisms to prevent the induction of inflammation. The retinal …

T cell-mediated autoimmunity in glaucoma neurodegeneration

L Wang, X Wei - Frontiers in Immunology, 2021 - frontiersin.org
Glaucoma as the leading neurodegenerative disease leads to blindness in 3.6 million
people aged 50 years and older worldwide. For many decades, glaucoma therapy has …

Transplantation of retinal pigment epithelial cells and immune response in the subretinal space.

X Zhang, D Bok - Investigative Ophthalmology & Visual …, 1998 - iovs.arvojournals.org
PURPOSE: To evaluate the fate of retinal pigment epithelial cell (RPE) allografts in the
subretinal space. METHODS: Transplantation was performed in Royal College of Surgeons …

Uveitis: pathogenesis.

JV Forrester - The Lancet, 1991 - elibrary.ru
Discusses the change in emphasis regarding endogenous uveitis which has now shifted
towards immunological, if not autoimmune, mechanisms, but states that infection is still …

Flow cytometric identification of a minority population of MHC class II positive cells in the normal rat retina distinct from CD45lowCD11b/c+ CD4low parenchymal …

AD Dick, AL Ford, JV Forrester… - British journal of …, 1995 - bjo.bmj.com
AIMS--This study aimed to isolate and classify by flow cytometry, the cell surface phenotype
of microglia in the normal rat retina with a view to identifying putative antigen presenting …