Crosstalk between aging, circadian rhythm, and melatonin

AK Verma, MI Khan, F Ashfaq, SI Rizvi - Rejuvenation Research, 2023 - liebertpub.com
Circadian rhythms (CRs) are 24-hour periodic oscillations governed by an endogenous
circadian pacemaker located in the suprachiasmatic nucleus (SCN), which organizes the …

Melatonin mitigates disrupted circadian rhythms, lowers intraocular pressure, and improves retinal ganglion cells function in glaucoma

D Gubin, V Neroev, T Malishevskaya… - Journal of Pineal …, 2021 - Wiley Online Library
Glaucoma is a progressive optic neuropathy associated with damage to retinal ganglion
cells (RGCs) and disrupted circadian rhythms. Melatonin is a promising substance to …

Age-dependent changes of the temporal order-causes and treatment

DG Gubin, D Weinert, TV Bolotnova - Current aging science, 2016 - ingentaconnect.com
This review summarizes current knowledge on deteriorations in temporal order with
advanced age. Changes of the overt rhythms will be described but also their putative causes …

Activity, sleep and ambient light have a different impact on circadian blood pressure, heart rate and body temperature rhythms

DG Gubin, D Weinert, SV Rybina… - Chronobiology …, 2017 - Taylor & Francis
The aim of the present study was to investigate the impact of endogenous and exogenous
factors for the expression of the daily rhythms of body temperature (BT), blood pressure (BP) …

Daily melatonin administration attenuates age-dependent disturbances of cardiovascular rhythms

DG Gubin, GD Gubin, LI Gapon… - Current aging …, 2016 - ingentaconnect.com
Increased blood pressure and reduced robustness of circadian rhythms are frequently
reported in elderly subjects. The present study was aimed to investigate whether such …

Disrupted circadian rhythms of body temperature, heart rate and fasting blood glucose in prediabetes and type 2 diabetes mellitus

DG Gubin, AA Nelaeva, AE Uzhakova… - Chronobiology …, 2017 - Taylor & Francis
We report a progressive disruption of 24-h rhythms in fasting blood glucose (FBG), body
temperature (BT) and heart rate (HR) associated with metabolic dysfunction and the …

[HTML][HTML] Disruption of 24-hour rhythm in intraocular pressure correlates with retinal ganglion cell loss in glaucoma

V Neroev, T Malishevskaya, D Weinert… - International journal of …, 2020 - mdpi.com
Parameters of 24-h rhythm in intraocular pressure (IOP) were assessed in patients with
stable or advanced primary open-angle glaucoma (S-POAG/A-POAG) and referenced to the …

Chronotype and lipid metabolism in Arctic Sojourn Workers

D Gubin, A Vetoshkin, N Shurkevich… - Chronobiology …, 2023 - Taylor & Francis
This study relates answers to the Munich Chronotype Questionnaire (MCTQ) and Pittsburgh
Sleep Quality Index (PSQI) from Arctic Sojourn Workers (ASW) of Yamburg Settlement, 68° …

Melatonin attenuates light-at-night effects on systolic blood pressure and body temperature but does not affect diastolic blood pressure and heart rate circadian …

D Gubin, D Weinert, SV Solovieva… - Biological Rhythm …, 2020 - Taylor & Francis
Aim of the present study is to assess whether 1.5 mg of exogenous melatonin provided
under modified CR in constant light (~ 400 lx) is capable to mimic effects of dark phase. Forty …

Точность биологических часов, хронотип, здоровье и долголетие

ДГ Губин, СН Коломейчук - Хрономедицинский журнал, 2019 - elibrary.ru
Предложено обоснование взаимосвязи между точностью хода циркадианных
биологических часов, хронотипом и здоровьем. На примере разных видов животных, а …