Exosomes as biomarkers and therapeutic delivery for autoimmune diseases: opportunities and challenges

Y Fang, J Ni, YS Wang, Y Zhao, LQ Jiang, C Chen… - Autoimmunity …, 2023 - Elsevier
Exosomes are spherical lipid bilayer vesicles composed of lipids, proteins and nucleic acids
that deliver signaling molecules through a vesicular transport system to regulate the function …

[HTML][HTML] Macrophages in lupus nephritis: exploring a potential new therapeutic avenue

LE Kwant, Y Vegting, MWP Tsang-a-Sjoe… - Autoimmunity …, 2022 - Elsevier
Lupus nephritis (LN) is a serious complication of systemic lupus erythematosus (SLE) that
occurs in about half of patients. LN is characterized by glomerular deposition of immune …

Type I interferons in systemic lupus erythematosus: a journey from bench to bedside

TM Sim, SJ Ong, A Mak, SH Tay - International Journal of Molecular …, 2022 - mdpi.com
Dysregulation of type I interferons (IFNs) has been implicated in the pathogenesis of
systemic lupus erythematosus (SLE) since the late 1970s. The majority of SLE patients …

[HTML][HTML] Locus coeruleus tyrosine hydroxylase positive neurons mediated the peripheral and central therapeutic effects of transcutaneous auricular vagus nerve …

H Lv, X Yu, P Wang, M Luo, Y Luo, H Lu, K Wang, A Xi… - Brain Stimulation, 2024 - Elsevier
Objective This study aims to investigate the effects of transcutaneous auricular vagus nerve
stimulation (taVNS) on the development of systemic lupus erythematosus (SLE) in MRL/lpr …

Risk of systemic lupus erythematosus flares according to autoantibody positivity at the time of diagnosis

OC Kwon, MC Park - Scientific Reports, 2023 - nature.com
To estimate the risk of systemic lupus erythematosus (SLE) flares based on the autoantibody
positivity at the time of SLE diagnosis. This retrospective cohort study included 228 patients …

Exosomes as crucial players in pathogenesis of systemic lupus erythematosus

Y Fei, Q Liu, N Peng, G Yang, Z Shen… - Journal of …, 2022 - Wiley Online Library
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that affects multiple
systems. Its clinical manifestation varies across patients, from skin mucosa to multiorgan …

Exploring the Molecular Mechanisms and Shared Gene Signatures Between Systemic Lupus Erythematosus and Bladder Urothelial Carcinoma

K Wang, S Wang, Y Ding, Z Kou, B Jiang… - International Journal of …, 2024 - Taylor & Francis
Background Systemic lupus erythematosus (SLE) is a chronic autoimmune disease
associated with increased susceptibility to cancer, including bladder urothelial carcinoma …

Multi-omic biomarkers for patient stratification in sjogren's syndrome—a review of the literature

L Martin-Gutierrez, R Wilson, M Castelino, EC Jury… - Biomedicines, 2022 - mdpi.com
Sjögren's syndrome (SS) is a heterogeneous autoimmune rheumatic disease (ARD)
characterised by dryness due to the chronic lymphocytic infiltration of the exocrine glands …

Development of the American College of Rheumatology Patient‐Reported Outcome Quality Measures for Systemic Lupus Erythematosus

PP Katz, CEH Barber, A Duarte‐García… - Arthritis Care & …, 2024 - Wiley Online Library
Objective As part of a Centers for Disease Control and Prevention–funded American
College of Rheumatology (ACR) initiative, we sought to develop quality measures related to …

Quantitative assessment of retinal vasculature changes in systemic lupus erythematosus using wide-field OCTA and the correlation with disease activity

L Meng, L Chen, C Zhang, H Chen, J Yang… - Frontiers in …, 2024 - frontiersin.org
Purpose To assess the retinal vasculature changes quantitatively using wide-field optical
coherence tomography angiography (OCTA) in systemic lupus erythematosus (SLE), and …