Alloxan and streptozotocin are widely used to induce experimental diabetes in animals. The
mechanism of their action in B cells of the pancreas has been intensively investigated and …

Diabetes mellitus is a potentially morbid condition with high prevalence worldwide thus the
disease constitutes a major health concern. Presently, it is an incurable metabolic disorder …

Plant stress responses are a key factor in steering the development of cells, tissues, and
organs. However, the stress-induced signal transduction cascades that control localized …

Inositol-requiring transmembrane kinase/endoribonuclease 1α (IRE1α) is the most
prominent and evolutionarily conserved endoplasmic reticulum (ER) membrane protein …

Diabetes mellitus is a potentially morbid condition with high prevalence worldwide thus
being a major medical concern. Experimental induction of diabetes mellitus in animal …

Pancreatic islets contain low activities of catalase, selenium-dependent glutathione
peroxidase 1 (GPX1), and Cu, Zn-superoxide dismutase 1 (SOD1). Thus, enhancing …

In the present study, we aimed to investigate the protective effect of ferulic acid at different
doses (50 mg/kg alternative day and 50 mg/kg daily) on diabetic rats and to explore the …

Aqueous extract of leaves of 3 herbs (Murraya koenigii, MK; Psidium guajava, PG and
Catharanthus roseus, CR) were used to test their antidiabetic activity in Streptozotocin (STZ) …

Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by hyperglycemia
due to progressive immune-mediated destruction of insulin-producing pancreatic islet β …

Type 1 diabetes (T1D) is a chronic autoimmune disease in which pancreatic islet β cells are
destroyed by immune cells, ultimately leading to overt diabetes. The progressive increase in …