This review encompasses the most important advances in liver functions and hepatotoxicity
and analyzes which mechanisms can be studied in vitro. In a complex architecture of nested …

Drug-induced acute liver failure carries a high morbidity and mortality rate. Acetaminophen
overdose is the number one cause of acute liver failure and remains a major problem in …

Background & Aims Machine perfusion is a novel method intended to optimize livers before
transplantation. However, its effect on morbidity within a 1-year period after transplantation …

Chemokines are small proteins that control several tissue functions, including cell
recruitment and activation under homeostatic and inflammatory conditions. CXCL8 …

Ischemia-reperfusion injury is an important cause of liver damage occurring during surgical
procedures including hepatic resection and liver transplantation, and represents the main …

Hepatotoxicity is a serious problem during drug development and for the use of many
established drugs. For example, acetaminophen overdose is currently the most frequent …

Ischemia-reperfusion injury is an important cause of liver damage occurring during surgical
procedures including hepatic resection and liver transplantation, and represents the main …

Organelle-targeted photosensitization represents a promising approach in photodynamic
therapy where the design of the active photosensitizer (PS) is very crucial. In this work, we …

The discovery that mammalian cells have the ability to synthesize the free radical nitric oxide
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …

The possibility of safe discontinuation of therapy with nucleos (t) ide analogues (NAs)
remains one of the most controversial topics in the management of chronic hepatitis B …