Bioinspired approaches to toughen calcium phosphate-based ceramics for bone repair.

P Dee, HY You, SH Teoh, H Le Ferrand - Journal of the Mechanical …, 2020 - Elsevier
To respond to the increasing need for bone repair strategies, various types of biomaterials
have been developed. Among those, calcium phosphate (CaP) ceramics are promising …

Sol–gel synthesis of calcium phosphate-based biomaterials—A review of environmentally benign, simple, and effective synthesis routes

K Ishikawa, E Garskaite, A Kareiva - Journal of Sol-Gel Science and …, 2020 - Springer
In this review article the available results about application of sol–gel synthesis method for
the preparation of different calcium phosphates and composite materials are summarized …

In vitro study on the degradation of lithium-doped hydroxyapatite for bone tissue engineering scaffold

Y Wang, X Yang, Z Gu, H Qin, L Li, J Liu… - Materials Science and …, 2016 - Elsevier
Li-doped hydroxyapatite (LiHA) which is prepared through introducing low dose of Li into
hydroxyapatite (HA) has been increasingly studied as a bone tissue-engineered scaffold …

Modulation of 3D printed calcium-deficient apatite constructs with varying Mn concentrations for osteochondral regeneration via endochondral differentiation

M Kamaraj, UK Roopavath, PS Giri… - … Applied Materials & …, 2022 - ACS Publications
Osteochondral regeneration remains a vital problem in clinical situations affecting both bone
and cartilage tissues due to the low regeneration ability of cartilage tissue. Additionally, the …

Study of physico-mechanical and electrical properties of cerium doped hydroxyapatite for biomedical applications

A Nisar, S Iqbal, MAU Rehman, A Mahmood… - Materials Chemistry and …, 2023 - Elsevier
The hydroxyapatite-based cerium-doped ceramics (Ce-HAp) were synthesized by the wet
precipitation method. The mechanical and dielectric properties were investigated by density …

Strategies of strengthening mechanical properties in the osteoinductive calcium phosphate bioceramics

Q Li, C Feng, Q Cao, W Wang, Z Ma… - Regenerative …, 2023 - academic.oup.com
Calcium phosphate (CaP) bioceramics are widely applied in the bone repairing field
attributing to their excellent biological properties, especially osteoinductivity. However, their …

Cationic substitution effects in phosphate-based bioceramics-A way towards superior bioproperties

L Lukaviciute, R Ganceviciene, K Tsuru, K Ishikawa… - Ceramics …, 2024 - Elsevier
This review summarises the available results on the effects of cation substitution on the
antibacterial and other bioproperties of different phosphates. Attention is given to bulk cation …

Tricalcium phosphate doped with Mg2+ and combinations of Mn2+, Zn2+ and Fe3+: A DoE study on sintering, mechanical, microstructural and biological properties

DF Macedo, AF Cunha, JF Mano, MB Oliveira… - Ceramics …, 2022 - Elsevier
Bioactive ceramics such as tricalcium phosphate (TCP) doped with metal ions are often
used to replace natural bone in orthopedic and dental function, both in structural and coating …

In vivo evaluation of porous lithium-doped hydroxyapatite scaffolds for the treatment of bone defect

Y Luo, D Li, J Zhao, Z Yang… - Bio-medical materials …, 2018 - content.iospress.com
Hydroxyapatite (HA) possesses similar mineral components to bone and possesses good
physicochemical properties. Even though pure HA scaffold is brittle, it is insufficient in …

The effects of Mn and/or Ni dopants on the in vitro/in vivo performance, structural and magnetic properties of β-tricalcium phosphate bioceramics

T Ates, SV Dorozhkin, O Kaygili, M Kom, I Ercan… - Ceramics …, 2019 - Elsevier
The present study describes the effects of dopants of Mn and/or Ni on the structural,
magnetic and in vivo/in vitro performances of β-tricalcium phosphate (β-TCP) bioceramics …