Summary Each year, the American Heart Association (AHA), in conjunction with the National
Institutes of Health and other government agencies, brings together in a single document the …

Summary Each year, the American Heart Association (AHA), in conjunction with the Centers
for Disease Control and Prevention, the National Institutes of Health, and other government …

Objective To develop new antiphospholipid syndrome (APS) classification criteria with high
specificity for use in observational studies and trials, jointly supported by the American …

Background Rheumatic heart disease affects more than 40.5 million people worldwide and
results in 306,000 deaths annually. Echocardiographic screening detects rheumatic heart …

Background Rheumatic heart disease remains an important preventable cause of
cardiovascular death and disability, particularly in low-income and middle-income countries …

Acute rheumatic fever (ARF) is the result of an autoimmune response to pharyngitis caused
by infection with group A Streptococcus. The long-term damage to cardiac valves caused by …

Background—Acute rheumatic fever remains a serious healthcare concern for the majority of
the world's population despite its decline in incidence in Europe and North America. The …

Níveis de evidência Nível A Dados obtidos a partir de múltiplos estudos randomizados de
bom porte, concordantes e/ou de meta-análise robusta de estudos clínicos randomizados …

The global burden of rheumatic heart disease continues to be significant although it is
largely limited to poor and marginalized populations. In most endemic regions, affected …

Level of evidence Level A Data obtained from multiple concordant large randomized trials
and/or robust meta-analysis of randomized clinical trials Level B Data obtained from less …