Gut mucosal barriers, including chemical and physical barriers, spatially separate the gut
microbiota from the host immune system to prevent unwanted immune responses that could …

MicroRNAs (miRNAs) are naturally occurring noncoding RNAs with multiple functionalities.
They are dysregulated in several conditions and can serve as disease biomarkers …

Effective delivery of luminal antigens to the underlying immune system is the initial step in
generating antigen‐specific responses in the gut. However, a large body of information …

The gastrointestinal tract is a complex and important physiological and immunological organ
embodying the first line of defense by which mucosal immunity regulates the immense …

The role of miRNAs in intestinal lipid metabolism is poorly described. The small intestine is
constantly exposed to high amounts of dietary lipids, and it is under conditions of stress that …

Intestinal helminth infections are highly prevalent in the developing world, often resulting in
chronic infection and inflicting high host morbidity. With the emergence of drug‐resistant …

The rapid self-renewal of intestinal epithelial cells enhances intestinal function, promotes the
nutritional needs of animals and strengthens intestinal barrier function to resist the invasion …

This article reviews the field of oral uptake of nanoparticles across the gastrointestinal
epithelium for the period 2006–2016. Analysis is conducted from the viewpoint of i) M-cell …

Immune responses against gut microbiota should be minimized to avoid unnecessary
inflammation at mucosal surface. In this study, we analyzed the expression patterns of Toll …

Epithelial cells (ECs) provide the first line of defense against microbial threats and
environmental challenges. They participate in the host's immune responses via the …