Dementia prevention, intervention, and care: 2020 report of the Lancet Commission
Executive summary The number of older people, including those living with dementia, is
rising, as younger age mortality declines. However, the age-specific incidence of dementia …
rising, as younger age mortality declines. However, the age-specific incidence of dementia …
The quest to slow ageing through drug discovery
L Partridge, M Fuentealba, BK Kennedy - Nature Reviews Drug …, 2020 - nature.com
Although death is inevitable, individuals have long sought to alter the course of the ageing
process. Indeed, ageing has proved to be modifiable; by intervening in biological systems …
process. Indeed, ageing has proved to be modifiable; by intervening in biological systems …
Aspirin use to prevent cardiovascular disease and colorectal cancer: updated evidence report and systematic review for the US preventive services task force
JM Guirguis-Blake, CV Evans, LA Perdue, SI Bean… - Jama, 2022 - jamanetwork.com
Importance Low-dose aspirin is used for primary cardiovascular disease prevention and
may have benefits for colorectal cancer prevention. Objective To review the benefits and …
may have benefits for colorectal cancer prevention. Objective To review the benefits and …
American Geriatrics Society 2019 updated AGS Beers Criteria® for potentially inappropriate medication use in older adults
2019 American Geriatrics Society Beers … - Journal of the …, 2019 - Wiley Online Library
The American Geriatrics Society (AGS) Beers Criteria®(AGS Beers Criteria®) for Potentially
Inappropriate Medication (PIM) Use in Older Adults are widely used by clinicians, educators …
Inappropriate Medication (PIM) Use in Older Adults are widely used by clinicians, educators …
[HTML][HTML] Cancer prevention with aspirin in hereditary colorectal cancer (Lynch syndrome), 10-year follow-up and registry-based 20-year data in the CAPP2 study: a …
Background Lynch syndrome is associated with an increased risk of colorectal cancer and
with a broader spectrum of cancers, especially endometrial cancer. In 2011, our group …
with a broader spectrum of cancers, especially endometrial cancer. In 2011, our group …
Effect of aspirin on cardiovascular events and bleeding in the healthy elderly
Background Aspirin is a well-established therapy for the secondary prevention of
cardiovascular events. However, its role in the primary prevention of cardiovascular disease …
cardiovascular events. However, its role in the primary prevention of cardiovascular disease …
Effect of aspirin on all-cause mortality in the healthy elderly
Background In the primary analysis of the Aspirin in Reducing Events in the Elderly
(ASPREE) trial, now published in the Journal, we report that the daily use of aspirin did not …
(ASPREE) trial, now published in the Journal, we report that the daily use of aspirin did not …
Role of AMPK mediated pathways in autophagy and aging
Y Ge, M Zhou, C Chen, X Wu, X Wang - Biochimie, 2022 - Elsevier
AMPK is an important kinase regulating energy homeostasis and also a key protein involved
in a variety of signal transduction pathways. It plays a vitally regulatory role in cellular …
in a variety of signal transduction pathways. It plays a vitally regulatory role in cellular …
Chinese Stroke Association guidelines for clinical management of cerebrovascular disorders: executive summary and 2019 update of clinical management of …
Aim Stroke is the leading cause of disability and death in China. Ischaemic stroke accounts
for about 60%–80% of all strokes. It is of considerable significance to carry out …
for about 60%–80% of all strokes. It is of considerable significance to carry out …
[HTML][HTML] Ten things to know about ten cardiovascular disease risk factors
Given rapid advancements in medical science, it is often challenging for the busy clinician to
remain up-to-date on the fundamental and multifaceted aspects of preventive cardiology and …
remain up-to-date on the fundamental and multifaceted aspects of preventive cardiology and …