RNA-based diagnostic and therapeutic strategies for cardiovascular disease
D Lu, T Thum - Nature Reviews Cardiology, 2019 - nature.com
Cardiovascular diseases are the leading cause of death globally and are associated with
increasing financial expenditure. With the availability of next-generation sequencing …
increasing financial expenditure. With the availability of next-generation sequencing …
miRNAs; a novel strategy for the treatment of COVID‐19
H Ying, M Ebrahimi, M Keivan… - Cell biology …, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is the seventh member of the bat severe
acute respiratory syndrome family. COVID‐19 can fuse their envelopes with the host cell …
acute respiratory syndrome family. COVID‐19 can fuse their envelopes with the host cell …
Circulating cardiovascular microRNAs in critically ill COVID‐19 patients
A Garg, B Seeliger, AA Derda, K Xiao… - European journal of …, 2021 - Wiley Online Library
Abstract Aims Coronavirus disease 2019 (COVID‐19) is a still growing pandemic, causing
many deaths and socio‐economic damage. Elevated expression of the severe acute …
many deaths and socio‐economic damage. Elevated expression of the severe acute …
[HTML][HTML] Ginsenoside Rg1 ameliorates blood–brain barrier disruption and traumatic brain injury via attenuating macrophages derived exosomes miR-21 release
K Zhai, H Duan, W Wang, S Zhao, GJ Khan… - … Pharmaceutica Sinica B, 2021 - Elsevier
During the traumatic brain injury (TBI), improved expression of circulatory miR-21 serves as
a diagnostic feature. Low levels of exosome-miR-21 in the brain can effectively improve …
a diagnostic feature. Low levels of exosome-miR-21 in the brain can effectively improve …
Angiogenic endothelial cell signaling in cardiac hypertrophy and heart failure
R Gogiraju, ML Bochenek, K Schäfer - Frontiers in cardiovascular …, 2019 - frontiersin.org
Endothelial cells are, by number, one of the most abundant cell types in the heart and active
players in cardiac physiology and pathology. Coronary angiogenesis plays a vital role in …
players in cardiac physiology and pathology. Coronary angiogenesis plays a vital role in …
Targeting miR-126 in inv (16) acute myeloid leukemia inhibits leukemia development and leukemia stem cell maintenance
L Zhang, LXT Nguyen, YC Chen, D Wu… - Nature …, 2021 - nature.com
Acute myeloid leukemia (AML) harboring inv (16)(p13q22) expresses high levels of miR-
126. Here we show that the CBFB-MYH11 (CM) fusion gene upregulates miR-126 …
126. Here we show that the CBFB-MYH11 (CM) fusion gene upregulates miR-126 …
MiR155-5p in adventitial fibroblasts-derived extracellular vesicles inhibits vascular smooth muscle cell proliferation via suppressing angiotensin-converting enzyme …
Proliferation of vascular smooth muscle cells (VSMCs) plays crucial roles in vascular
remodelling and stiffening in hypertension. Vascular adventitial fibroblasts are a key …
remodelling and stiffening in hypertension. Vascular adventitial fibroblasts are a key …
Role of miRNAs as biomarkers of COVID-19: A scoping review of the status and future directions for research in this field
MB Visacri, AS Nicoletti, EC Pincinato… - Biomarkers in …, 2021 - Taylor & Francis
Aim: miRNAs are potential biomarkers of several diseases. This review aimed to identify the
miRNAs that could serve as biomarkers of COVID-19. Materials & methods: A literature …
miRNAs that could serve as biomarkers of COVID-19. Materials & methods: A literature …
Strategies and challenges for non-viral delivery of non-coding RNAs to the heart
A Vilaça, LJ de Windt, H Fernandes… - Trends in Molecular …, 2023 - cell.com
Abstract Non‐coding RNAs (ncRNAs), such as miRNAs and long non‐coding RNAs
(lncRNAs) have been reported as regulators of cardiovascular pathophysiology. Their …
(lncRNAs) have been reported as regulators of cardiovascular pathophysiology. Their …
Myofibroblast-derived exosome induce cardiac endothelial cell dysfunction
Background: Endothelial cells (ECs) play a critical role in the maintenance of vascular
homeostasis and in heart function. It was shown that activated fibroblast-derived exosomes …
homeostasis and in heart function. It was shown that activated fibroblast-derived exosomes …