The developing mammalian cerebral cortex contains a distinct class of cells, subplate
neurons (SPns), that play an important role during early development. SPns are the first …

Neuronal migration is a fundamental process in central nervous system (CNS) development.
The assembly of functioning neuronal circuits relies on neuronal migration occurring in the …

Microglia are observed in the early developing forebrain and contribute to the regulation of
neurogenesis through still unravelled mechanisms. In the developing cerebral cortex …

Measuring serum androgen levels in women has been challenging due to limitations in
method accuracy, precision sensitivity and specificity at low hormone levels. The clinical …

Chemotactic cytokines (chemokines) have been traditionally defined as small (10–14kDa)
secreted leukocyte chemoattractants. However, chemokines and their cognate receptors are …

Chemokines are not only found in the immune system or expressed in inflammatory
conditions: they are constitutively present in the brain in both glial cells and neurons …

Chronic (neuropathic) pain is one of the most widespread and intractable of human
complaints, as well as being one of the most difficult syndromes to treat successfully with …

Stromal cell-derived factor-1 is a chemoattractant produced by bone marrow stromal cell
lines. It is recognized as a critical factor in the immune and central nervous systems (CNSs) …

Cajal-Retzius cells are critical in the development of the cerebral cortex, but little is known
about the mechanisms controlling their development. Three focal sources of Cajal-Retzius …

Lamination of neurons and fibre projections is a fundamental organizational principle of the
mammalian cerebral cortex. A laminated organization is likely to be essential for cortical …