Rapid changes in the viral genome allow viruses to evade threats posed by the host immune
response or antiviral drugs, and can lead to viral persistence in the host cells. RNA …

The global pandemic of Coronavirus Disease 2019 (COVID-19) has brought the world to a
grinding halt. A major cause of concern is the respiratory distress associated mortality …

The nitro group is considered to be a versatile and unique functional group in medicinal
chemistry. Despite a long history of use in therapeutics, the nitro group has toxicity issues …

Giardia is the commonest parasitic diarrheal pathogen affecting humans and a frequent
cause of waterborne/foodborne parasitic diseases worldwide. Prevalence of giardiasis is …

The use of chemotherapeutic drugs is the main resource against clinical giardiasis due to
the lack of approved vaccines. Resistance of G. duodenalis to the most used drugs to treat …

Giardia parasites are ubiquitous protozoans of global importance that impact a wide range
of animals including humans. They are the most common enteric pathogen of cats and dogs …

Giardia intestinalis infection causes enterocytes damage and loss of brush border of the
epithelial cells of the intestine that leads to shortening of microvilli and altered epithelial …

Inflammation is a hallmark of many diseases, including cancer, neurodegenerative diseases
like Alzheimer's, type II diabetes, rheumatoid arthritis, and asthma. Nonsteroidal anti …

Leishmaniasis is a group of vector-borne, parasitic diseases caused by over 20 species of
the protozoan Leishmania spp. The three major disease classifications, cutaneous, visceral …

Trypanosomiasis is caused by parasitic protozoan trypanosomes in vertebrates. T. cruzi and
T. brucei are causative agents of Chagas disease (CD) and Human African …