The incidence of type 2 diabetes mellitus (T2DM) has increased in our society in recent
decades as the population ages, and this trend is not expected to revert. This is the same for …

All cells rely on nutrients to supply energy and carbon building blocks to support cellular
processes. Over time, eukaryotes have developed increasingly complex systems to integrate …

The existing literature points towards the presence of robust mitochondrial mechanisms
aimed at mitigating protein dyshomeostasis within the organelle. However, the precise …

Inorganic polyphosphate (polyP) is an ancient biopolymer that is well preserved throughout
evolution and present in all studied organisms. In mammals, it shows a high co-localization …

Inorganic polyphosphate (polyP) is an evolutionarily conserved and ubiquitous polymer that
is present in all studied organisms. PolyP consists of orthophosphates (Pi) linked together by …

Inorganic polyphosphate (polyP) is an ancient, ubiquitous, and well-conserved polymer
which is present in all the studied organisms. It is formed by individual subunits of …

Inorganic polyphosphate (polyP), the polymeric form of phosphate, is attracting ever-growing
attention due to the many functions it appears to perform within mammalian cells. This essay …

Alzheimer's Disease (AD) is the most common neurodegenerative disorder in our society, as
the population ages, its incidence is expected to increase in the coming decades. The …

Fetal alcohol spectrum disorder (FASD) includes neuropsychiatric disturbances related to
gestational and lactational ethanol exposure. Available treatments are minimal and do not …

Inorganic polyphosphate (polyP), the first high-energy compound on earth, defies its
extreme compositional and structural simplicity with an astoundingly wide array of biological …