Hypertension is a worldwide problem with major impacts on health including morbidity and
mortality, as well as consumption of health care resources. Nearly 50% of American adults …

The gut microbiome and intestinal dysfunction have emerged as potential contributors to the
development of cardiovascular disease (CVD). Alterations in gut microbiome are well …

Ischemic stroke is a highly complex and devastating neurological disease. The sudden loss
of blood flow to a brain region due to an ischemic insult leads to severe damage to that area …

Cardiovascular diseases (CVDs) make a substantial contribution to the global burden of
disease. Prevention strategies have succeeded in reducing the effect of acute CVD events …

The close association among cardiovascular, metabolic, and kidney diseases suggests a
common pathological basis and significant interaction among these diseases. Metabolic …

Vagal afferent neuron (VAN) signaling sends information from the gut to the brain and is
fundamental in the control of feeding behavior and metabolism [1]. Recent findings reveal …

Excessive activation of the sympathetic nervous system is one of the pathophysiological
hallmarks of hypertension and heart failure. Within the central nervous system, the …

The sympathetic nervous system plays a critical role in the pathogenesis of hypertension.
The central nervous system (CNS) organizes the sympathetic outflow and various inputs …

Background: The neuroinflammatory process is associated with the pathogenesis of many
cardiovascular disorders, particularly with hypertension. In this regard, the deficiency of …

Augmented vagal signaling may be therapeutic in hypertension. Most studies to date have
used stimulation of the cervical vagal branches. Here, we investigated the effects of chronic …