Metal-catalysed C–H bond activation and borylation
Transition metal-catalysed direct borylation of hydrocarbons via C–H bond activation has
received a remarkable level of attention as a popular reaction in the synthesis of …
received a remarkable level of attention as a popular reaction in the synthesis of …
Transition metal catalysis controlled by hydrogen bonding in the second coordination sphere
Transition metal catalysis is of utmost importance for the development of sustainable
processes in academia and industry. The activity and selectivity of metal complexes are …
processes in academia and industry. The activity and selectivity of metal complexes are …
Strategic evolution in transition metal-catalyzed directed C–H bond activation and future directions
In the field of C–H bond functionalization chemistry, directed C–H bond activation strategies
are highly appreciated due to the high efficiency and selectivity of such reactions towards a …
are highly appreciated due to the high efficiency and selectivity of such reactions towards a …
Transition metal–catalyzed remote C─ H borylation: An emerging synthetic tool
MMM Hassan, S Guria, S Dey, J Das… - Science …, 2023 - science.org
Transition metal–catalyzed C─ H bond activation and borylation is a powerful synthetic
method that offers versatile synthetic transformation from organoboron compounds to …
method that offers versatile synthetic transformation from organoboron compounds to …
Arene diversification through distal C(sp2)−H functionalization
BACKGROUND Organic synthetic chemistry has facilitated the production of medicines,
agrochemicals, food, polymers, dyes, and more through step-and atom-economical …
agrochemicals, food, polymers, dyes, and more through step-and atom-economical …
Synthesis of planar chiral ferrocenes via enantioselective remote C–H activation
L Zhou, HG Cheng, L Li, K Wu, J Hou, C Jiao… - Nature Chemistry, 2023 - nature.com
Planar chiral ferrocenes are widely studied structures in asymmetric catalysis, materials
science and medicinal chemistry. Although synthetic methods for 1, 2-disubstituted planar …
science and medicinal chemistry. Although synthetic methods for 1, 2-disubstituted planar …
Remote steric control for undirected meta-selective C–H activation of arenes
Regioselective functionalization of arenes remains a challenging problem in organic
synthesis. Steric interactions are often used to block sites adjacent to a given substituent, but …
synthesis. Steric interactions are often used to block sites adjacent to a given substituent, but …
Strategies that utilize ion pairing interactions to exert selectivity control in the functionalization of C–H bonds
JE Gillespie, A Fanourakis… - Journal of the American …, 2022 - ACS Publications
Electrostatic attraction between two groups of opposite charge, typically known as ion-
pairing, offers unique opportunities for the design of systems to enable selectivity control in …
pairing, offers unique opportunities for the design of systems to enable selectivity control in …
Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learning
Late-stage functionalization is an economical approach to optimize the properties of drug
candidates. However, the chemical complexity of drug molecules often makes late-stage …
candidates. However, the chemical complexity of drug molecules often makes late-stage …
Chiral transient directing groups in transition-metal-catalyzed enantioselective C–H bond functionalization
MI Lapuh, S Mazeh, T Besset - ACS Catalysis, 2020 - ACS Publications
Transition-metal-catalyzed C–H bond functionalization has known a rapid evolution in the
last years, offering modern strategies for reaching high molecular complexity in a step-and …
last years, offering modern strategies for reaching high molecular complexity in a step-and …