Melatonin mitigates mitochondrial meltdown: interactions with SIRT3
Melatonin exhibits extraordinary diversity in terms of its functions and distribution. When
discovered, it was thought to be uniquely of pineal gland origin. Subsequently, melatonin …
discovered, it was thought to be uniquely of pineal gland origin. Subsequently, melatonin …
SARS-CoV-2 and other coronaviruses negatively influence mitochondrial quality control: beneficial effects of melatonin
Coronaviruses (CoVs) are a group of single stranded RNA viruses, of which some of them
such as SARS-CoV, MERS-CoV, and SARS-CoV-2 are associated with deadly worldwide …
such as SARS-CoV, MERS-CoV, and SARS-CoV-2 are associated with deadly worldwide …
Ischemic brain injury: New insights on the protective role of melatonin
Stroke represents one of the most common causes of brain's vulnerability for many millions
of people worldwide. The plethora of physiopathological events associated with brain …
of people worldwide. The plethora of physiopathological events associated with brain …
Melatonin and ischemic stroke: mechanistic roles and action
SS Andrabi, S Parvez… - … in Pharmacological and …, 2015 - Wiley Online Library
Stroke is one of the most devastating neurological disabilities and brain's vulnerability
towards it proves to be fatal and socio‐economic loss of millions of people worldwide …
towards it proves to be fatal and socio‐economic loss of millions of people worldwide …
[HTML][HTML] Pharmacological treatment of vascular dementia: a molecular mechanism perspective
H Kuang, ZF Zhou, YG Zhu, ZK Wan, MW Yang… - Aging and …, 2021 - ncbi.nlm.nih.gov
Vascular dementia (VaD) is a neurodegenerative disease, with cognitive dysfunction
attributable to cerebrovascular factors. At present, it is the second most frequently occurring …
attributable to cerebrovascular factors. At present, it is the second most frequently occurring …
Melatonin salvages lead‐induced neuro‐cognitive shutdown, anxiety, and depressive‐like symptoms via oxido‐inflammatory and cholinergic mechanisms
NA Omeiza, HA Abdulrahim, AI Alagbonsi… - Brain and …, 2021 - Wiley Online Library
Introduction Lead is the most used nonphysiological neurotoxic heavy metal in the world that
has been indicated to interfere with the cognitive and noncognitive processes via numerous …
has been indicated to interfere with the cognitive and noncognitive processes via numerous …
Transcriptional regulation of antioxidant enzymes activity and modulation of oxidative stress by melatonin in rats under cerebral ischemia/reperfusion conditions
ED Kryl'skii, TN Popova, OA Safonova, AO Stolyarova… - Neuroscience, 2019 - Elsevier
The article studies the effect of melatonin on the intensity of free radical oxidation, the
functioning of the enzymatic components of the antioxidant system and their transcriptional …
functioning of the enzymatic components of the antioxidant system and their transcriptional …
Edaravone attenuates oxidative stress induced by chronic cerebral hypoperfusion injury: role of ERK/Nrf2/HO-1 signaling pathway
D Zhang, Y Xiao, P Lv, Z Teng, Y Dong, Q Qi… - Neurological …, 2018 - Taylor & Francis
Objectives The potential protective effects and mechanisms of edaravone have not been
well elucidated in vascular dementia (VaD) induced by chronic cerebral hypoperfusion …
well elucidated in vascular dementia (VaD) induced by chronic cerebral hypoperfusion …
Capsaicin ameliorates the loosening of mitochondria-associated endoplasmic reticulum membranes and improves cognitive function in rats with chronic cerebral …
M Ouyang, Q Zhang, J Shu, Z Wang, J Fan… - Frontiers in Cellular …, 2022 - frontiersin.org
Based on accumulating evidence, vascular factors contribute to cognitive decline and
dementia. Mitochondrial dysfunction is the core pathophysiological mechanism …
dementia. Mitochondrial dysfunction is the core pathophysiological mechanism …
Short-and long-term protective effects of melatonin in a mouse model of sepsis-associated encephalopathy
M Ji, D Xia, L Zhu, X Zhu, X Zhou, J Xia, J Yang - Inflammation, 2018 - Springer
Brain dysfunction is a common complication after sepsis and is an independent risk factor for
a poor prognosis, which is partly attributed to the dysregulated inflammatory response and …
a poor prognosis, which is partly attributed to the dysregulated inflammatory response and …