Antiplasmodial natural products: an update

N Tajuddeen, FR Van Heerden - Malaria journal, 2019 - Springer
Background Malaria remains a significant public health challenge in regions of the world
where it is endemic. An unprecedented decline in malaria incidences was recorded during …

Bioactivity and pharmacological properties of α-mangostin from the mangosteen fruit: a review

G Chen, Y Li, W Wang, L Deng - Expert opinion on therapeutic …, 2018 - Taylor & Francis
ABSTRACT Introduction: α-Mangostin (α-MG) is the most representative xanthone isolated
from the pericarp of mangosteen, possessing extensive biological activities and …

Lessons from exploring chemical space and chemical diversity of propolis components

TD Tran, SM Ogbourne, PR Brooks… - International journal of …, 2020 - mdpi.com
Propolis is a natural resinous material produced by bees and has been used in folk
medicines since ancient times. Due to it possessing a broad spectrum of biological activities …

Pharmacology of mangostins and their derivatives: A comprehensive review

W Ming-Hui, KJ Zhang, GU Qin-Lan… - Chinese journal of …, 2017 - Elsevier
Abstract Mangosteen (Garcinia mangostana Linn.) is a well-known tropical tree indigenous
to Southeast Asia. Its fruit's pericarp abounds with a class of isoprenylated xanthones which …

Therapeutic Potential of Marine-Derived Cyclic Peptides as Antiparasitic Agents

R Ribeiro, L Costa, E Pinto, E Sousa, C Fernandes - Marine Drugs, 2023 - mdpi.com
Parasitic diseases still compromise human health. Some of the currently available
therapeutic drugs have limitations considering their adverse effects, questionable efficacy …

Nanoformulations of α-mangostin for cancer drug delivery system

L Meylina, M Muchtaridi, IM Joni, AFA Mohammed… - Pharmaceutics, 2021 - mdpi.com
Natural compounds are emerging as effective agents for the treatment of malignant
diseases. The active constituent of α-mangostin from the pericarp of Garcinia mangostana L …

Phytochemicals and Biological Activities of Garcinia morella (Gaertn.) Desr.: A Review

HN Murthy, D Dalawai, YH Dewir, A Ibrahim - Molecules, 2020 - mdpi.com
Garcinia morella (Gaertn.) Desr. is an evergreen tree that yields edible fruits, oil, and resin. It
is a source of “gamboge”, a gum/resin that has a wide range of uses. The fruits, leaves, and …

Anti-Acanthamoeba synergistic effect of chlorhexidine and Garcinia mangostana extract or α-mangostin against Acanthamoeba triangularis trophozoite and cyst …

S Sangkanu, W Mitsuwan, W Mahabusarakam… - Scientific reports, 2021 - nature.com
Acanthamoeba spp. can cause amoebic keratitis (AK). Chlorhexidine is effective for AK
treatment as monotherapy, but with a relative failure on drug bioavailability in the deep …

Investigating the ameliorative effect of alpha‐mangostin on development and existing pain in a rat model of neuropathic pain

M Ghasemzadeh Rahbardar, BM Razavi… - Phytotherapy …, 2020 - Wiley Online Library
Mangosteen fruit has been used for various disorders, including pain. The effects of alpha‐
mangostin, the main component of mangosteen, on the neuropathic pain caused by chronic …

Alpha-mangostin attenuates brain inflammation induced by peripheral lipopolysaccharide administration in C57BL/6J mice

MN Catorce, G Acero, J Pedraza-Chaverri… - Journal of …, 2016 - Elsevier
Neuroinflammation is an important feature in the pathogenesis and progression of
neurodegenerative diseases. Molecules with anti-inflammatory properties have been …