Curcumin and its derivatives in cancer therapy: Potentiating antitumor activity of cisplatin and reducing side effects

AJ Abadi, S Mirzaei, MK Mahabady… - Phytotherapy …, 2022 - Wiley Online Library
Curcumin is a phytochemical isolated from Curcuma longa with potent tumor‐suppressor
activity, which has shown significant efficacy in pre‐clinical and clinical studies. Curcumin …

[HTML][HTML] Renoprotective effect of the antioxidant curcumin: Recent findings

J Trujillo, YI Chirino, E Molina-Jijón… - Redox biology, 2013 - Elsevier
For years, there have been studies based on the use of natural compounds plant-derived as
potential therapeutic agents for various diseases in humans. Curcumin is a phenolic …

Curcumin: the Indian solid gold

BB Aggarwal, C Sundaram, N Malani… - The molecular targets and …, 2007 - Springer
Turmeric, derived from the plant Curcuma longa, is a gold-colored spice commonly used in
the Indian subcontinent, not only for health care but also for the preservation of food and as …

Anti-oxidative effects of curcumin on immobilization-induced oxidative stress in rat brain, liver and kidney

S Samarghandian, M Azimi-Nezhad… - Biomedicine & …, 2017 - Elsevier
Restraint stress has been indicated to induce oxidative damage in tissues. Several
investigations have reported that curcumin (CUR) may have a protective effect against …

An integrative view of cisplatin-induced renal and cardiac toxicities: Molecular mechanisms, current treatment challenges and potential protective measures

GJ Dugbartey, LJ Peppone, IAM de Graaf - Toxicology, 2016 - Elsevier
Cisplatin is currently one of the most widely-used chemotherapeutic agents against various
malignancies. Its clinical application is limited, however, by inherent renal and cardiac …

Role of oxidative and nitrosative stress in cisplatin-induced nephrotoxicity

YI Chirino, J Pedraza-Chaverri - Experimental and Toxicologic Pathology, 2009 - Elsevier
cis-Diamminedichloroplatinum (II)(cisplatin) is an important chemotherapeutic agent useful
in the treatment of several cancers; however, it has several side effects such as …

Selenium and high dose vitamin E administration protects cisplatin-induced oxidative damage to renal, liver and lens tissues in rats

M Nazıroǧlu, A Karaoğlu, AO Aksoy - Toxicology, 2004 - Elsevier
Cisplatin is one of the most active cytotoxic agents in the treatment of cancer but its clinical
use is associated with nephrotoxicity. Several studies suggest that supplementation with …

An integrative view of the pathophysiological events leading to cisplatin nephrotoxicity

PD Sánchez-González… - Critical reviews in …, 2011 - Taylor & Francis
Cisplatin is among the most effective chemotherapeutic agents against solid tumors.
Nephrotoxicity is the most common side effect of cisplatin chemotherapy, which limits the …

Agents ameliorating or augmenting the nephrotoxicity of cisplatin and other platinum compounds: a review of some recent research

BH Ali, MS Al Moundhri - Food and chemical toxicology, 2006 - Elsevier
Cisplatin (cis-diamminedichloroplatinum (II)) is an effective agent against various solid
tumours. Despite its effectiveness, the dose of cisplatin that can be administered is limited by …

Effects of lycopene against cisplatin-induced nephrotoxicity and oxidative stress in rats

A Atessahin, S Yilmaz, I Karahan, AO Ceribasi… - Toxicology, 2005 - Elsevier
The aim of this study was to investigate the effects of lycopene on cisplatin-induced
nephrotoxicity and oxidative stress in rats. Adult male Sprague–Dawley rats were randomly …