The trinity of COVID-19: immunity, inflammation and intervention

MZ Tay, CM Poh, L Rénia, PA MacAry… - Nature Reviews …, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the ongoing coronavirus disease 2019 (COVID-19) pandemic. Alongside investigations into …

Overview of immune response during SARS-CoV-2 infection: lessons from the past

VK Shah, P Firmal, A Alam, D Ganguly… - Frontiers in …, 2020 - frontiersin.org
After the 1918 flu pandemic, the world is again facing a similar situation. However, the
advancement in medical science has made it possible to identify that the novel infectious …

The molecular virology of coronaviruses

E Hartenian, D Nandakumar, A Lari, M Ly… - Journal of Biological …, 2020 - ASBMB
Few human pathogens have been the focus of as much concentrated worldwide attention as
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of COVID-19. Its …

Biochemical characterization of SARS-CoV-2 nucleocapsid protein

W Zeng, G Liu, H Ma, D Zhao, Y Yang, M Liu… - Biochemical and …, 2020 - Elsevier
The nucleocapsid (N) protein is an important antigen for coronavirus, which participate in
RNA package and virus particle release. In this study, we expressed the N protein of SARS …

Laboratory testing of SARS‐CoV, MERS‐CoV, and SARS‐CoV‐2 (2019‐nCoV): Current status, challenges, and countermeasures

Y Yan, L Chang, L Wang - Reviews in medical virology, 2020 - Wiley Online Library
Emerging and reemerging infectious diseases are global public concerns. With the outbreak
of unknown pneumonia in Wuhan, China in December 2019, a new coronavirus, SARS …

COVID-19 vaccine: where are we now and where should we go?

S Soleimanpour, A Yaghoubi - Expert review of vaccines, 2021 - Taylor & Francis
Introduction The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has
currently caused the pandemic with a high progressive speed and has been considered as …

Robust T cell response toward spike, membrane, and nucleocapsid SARS-CoV-2 proteins is not associated with recovery in critical COVID-19 patients

CJ Thieme, M Anft, K Paniskaki… - Cell Reports …, 2020 - cell.com
T cell immunity toward SARS-CoV-2 spike (S-), membrane (M-), and nucleocapsid (N-)
proteins may define COVID-19 severity. Therefore, we compare the SARS-CoV-2-reactive T …

Immunology of COVID‐19: mechanisms, clinical outcome, diagnostics, and perspectives—a report of the European Academy of Allergy and Clinical Immunology …

M Sokolowska, ZM Lukasik, I Agache, CA Akdis… - Allergy, 2020 - Wiley Online Library
With the worldwide spread of the novel severe acute respiratory syndrome coronavirus‐2
(SARS‐CoV‐2) resulting in declaration of a pandemic by the World Health Organization …

Development of a portable, ultra-rapid and ultra-sensitive cell-based biosensor for the direct detection of the SARS-CoV-2 S1 spike protein antigen

S Mavrikou, G Moschopoulou, V Tsekouras, S Kintzios - Sensors, 2020 - mdpi.com
One of the key challenges of the recent COVID-19 pandemic is the ability to accurately
estimate the number of infected individuals, particularly asymptomatic and/or early-stage …

Accessory proteins of SARS-CoV and other coronaviruses

DX Liu, TS Fung, KKL Chong, A Shukla, R Hilgenfeld - Antiviral research, 2014 - Elsevier
The huge RNA genome of SARS coronavirus comprises a number of open reading frames
that code for a total of eight accessory proteins. Although none of these are essential for …