Cell–matrix interactions in mammary gland development and breast cancer

J Muschler, CH Streuli - Cold Spring Harbor perspectives …, 2010 - cshperspectives.cshlp.org
The mammary gland is an organ that at once gives life to the young, but at the same time
poses one of the greatest threats to the mother. Understanding how the tissue develops and …

[HTML][HTML] Role of Cripto-1 during epithelial-to-mesenchymal transition in development and cancer

MC Rangel, H Karasawa, NP Castro, T Nagaoka… - The American journal of …, 2012 - Elsevier
Epithelial-to-mesenchymal transition (EMT) is a critical multistep process that converts
epithelial cells to more motile and invasive mesenchymal cells, contributing to body …

Molecular complexity of mammary glands development: a review of lactogenic differentiation in epithelial cells

MK Jena, FB Khan, SA Ali, A Abdullah… - Artificial cells …, 2023 - Taylor & Francis
The mammary gland is a dynamic organ with various physiological processes like cellular
proliferation, differentiation, and apoptosis during the pregnancy-lactation-involution cycle. It …

Netrin-1 simultaneously suppresses corneal inflammation and neovascularization

Y Han, Y Shao, Z Lin, YL Qu, H Wang… - … & visual science, 2012 - iovs.arvojournals.org
Purpose.: To investigate the effect of netrin-1 on alkali burn-induced corneal inflammation
and neovascularization. Methods.: The expression of netrin-1 and its receptors UNC5A …

[HTML][HTML] Differential expression of neurogenes among breast cancer subtypes identifies high risk patients

P Fernández-Nogueira, P Bragado, V Almendro… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The nervous system is now recognized to be a relevant component of the tumor
microenvironment. Receptors for neuropeptides and neurotransmitters have been identified …

A co-culture genome-wide RNAi screen with mammary epithelial cells reveals transmembrane signals required for growth and differentiation

A Burleigh, S McKinney, J Brimhall, D Yap… - Breast Cancer …, 2015 - Springer
Introduction The extracellular signals regulating mammary epithelial cell growth are of
relevance to understanding the pathophysiology of mammary epithelia, yet they remain …

Cripto-1 is a cell surface marker for a tumorigenic, undifferentiated subpopulation in human embryonal carcinoma cells

K Watanabe, MJ Meyer, L Strizzi, JM Lee… - Stem Cells, 2010 - academic.oup.com
Deregulation of stem cells is associated with the generation and progression of malignant
tumors. In addition, genes that are associated with early embryogenesis are frequently …

Axon guidance factor netrin-1 and its receptors regulate angiogenesis after cerebral ischemia

Q Ding, SJ Liao, J Yu - Neuroscience bulletin, 2014 - Springer
Neurogenesis and angiogenesis play important roles in functional recovery after ischemic
stroke. When cerebral ischemia occurs, axon regeneration can compensate for the loss of …

Netrin-1 increases proliferation and migration of renal proximal tubular epithelial cells via the UNC5B receptor

W Wang, WB Reeves… - American Journal of …, 2009 - journals.physiology.org
The cellular hallmark of kidney repair is a rapid proliferation of renal tubular epithelial cells
ultimately leading to the restoration of nephron structure and function. Netrin-1 was …

Targeting nodal and cripto-1: perspectives inside dual potential theranostic cancer biomarkers

A Sandomenico, M Ruvo - Current Medicinal Chemistry, 2019 - ingentaconnect.com
Background: Elucidating the mechanisms of recurrence of embryonic signaling pathways in
tumorigenesis has led to the discovery of onco-fetal players which have physiological roles …