The molecular mechanisms of virus-induced human cancers
G Ameya, DJ Birri - Microbial Pathogenesis, 2023 - Elsevier
Cancer is a serious public health problem globally. Many human cancers are induced by
viruses. Understanding of the mechanisms by which oncogenic (tumorigenic) viruses induce …
viruses. Understanding of the mechanisms by which oncogenic (tumorigenic) viruses induce …
HIV vaccine mystery and viral shell disorder
Hundreds of billions of dollars have been spent for over three decades in the search for an
effective human immunodeficiency virus (HIV) vaccine with no success. There are also at …
effective human immunodeficiency virus (HIV) vaccine with no success. There are also at …
Turning a Luffa protein into a self-assembled biodegradable nanoplatform for multitargeted cancer therapy
The peptide-derived self-assembly platform has attracted increasing attention for its great
potential to develop into multitargeting nanomedicines as well as its inherent …
potential to develop into multitargeting nanomedicines as well as its inherent …
Clinical and molecular properties of human immunodeficiency virus-related diffuse large B-cell lymphoma
Non-Hodgkin lymphoma is the most common malignancy affecting people living with HIV
(PLWH). Among its several subtypes, diffuse large B-cell lymphoma (DLBCL) is an important …
(PLWH). Among its several subtypes, diffuse large B-cell lymphoma (DLBCL) is an important …
Heparin and heparan sulfate proteoglycans promote HIV-1 p17 matrix protein oligomerization: computational, biochemical and biological implications
Abstract p17 matrix protein released by HIV+ cells interacts with leukocytes heparan sulfate
proteoglycans (HSPGs), CXCR1 and CXCR2 exerting different cytokine-like activities that …
proteoglycans (HSPGs), CXCR1 and CXCR2 exerting different cytokine-like activities that …
[HTML][HTML] Identification of amino acid residues critical for the B cell growth-promoting activity of HIV-1 matrix protein p17 variants
W He, P Mazzuca, W Yuan, K Varney, A Bugatti… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Background HIV-1 matrix protein p17 variants (vp17s) detected in HIV-1-infected patients
with non-Hodgkin's lymphoma (HIV-NHL) display, differently from the wild-type protein …
with non-Hodgkin's lymphoma (HIV-NHL) display, differently from the wild-type protein …
Virus-driven dysregulation of the BCR pathway: a potential mechanism for the high prevalence of HIV related B-cell lymphoma
Y Liang, X Chen, X Zhang, C Guo, Y Zhang - Annals of Hematology, 2024 - Springer
In people living with HIV (PLWH), the susceptibility to malignancies is notably augmented,
with lymphoma emerging as a predominant malignancy. Even in the antiretroviral therapy …
with lymphoma emerging as a predominant malignancy. Even in the antiretroviral therapy …
Pathomechanism of mutated and secreted retinoschisin in X-linked juvenile retinoschisis
K Plössl, V Schmid, K Straub, C Schmid… - Experimental eye …, 2018 - Elsevier
Mutations in the RS1 gene encoding retinoschisin cause X-linked juvenile retinoschisis
(XLRS), a hereditary retinal dystrophy in males. While most of the XLRS associated …
(XLRS), a hereditary retinal dystrophy in males. While most of the XLRS associated …
Targeted disruption of the BCL9/β-catenin interaction by endosomal-escapable nanoparticles functionalized with an E-cadherin-derived peptide
Abnormal activation of the Wnt/β-catenin signaling pathway, which underlies multiple
malignancies, promotes tumor progression; drugs that can block this pathway are therefore …
malignancies, promotes tumor progression; drugs that can block this pathway are therefore …
HIV-1 Structural Proteins or Cell-Signaling Factors? That Is the Question!
M Pellegrino, F Giordano, F De Amicis, M Marra… - Current Issues in …, 2024 - mdpi.com
The biological activity of structural HIV-1 proteins is not limited to ensuring a productive viral
infection but also interferes with cellular homeostasis through intra-and extracellular …
infection but also interferes with cellular homeostasis through intra-and extracellular …