Exosomes play a role as mediators of cell-to-cell communication, thus exhibiting pleiotropic
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …

Obesity is one of the major risk factors for the development of both impaired glucose
tolerance (IGT, or prediabetes) and type 2 diabetes (T2D), and its prevalence worldwide …

During the last decade, there has been great interest in elucidating the biological role of
extracellular vesicles (EVs), particularly, their hormone-like role in cell-to-cell …

Type 2 diabetes mellitus (T2DM) is characterized by tissue-specific insulin resistance and
pancreatic β-cell dysfunction, which result from the interplay of local abnormalities within …

Diabetes results from the inability of pancreatic islets to maintain blood glucose
concentrations within a normal physiological range. Clinical features are usually not …

Nonalcoholic steatohepatitis (NASH) is considered as a progressive form of nonalcoholic
fatty liver disease (NAFLD). To distinguish NASH from nonalcoholic fatty liver (NAFL), we …

Background Diabetic nephropathy (DN) is associated with high risk of cardiovascular
disease and mortality. Exosomal microRNAs (miRNAs) regulate gene expression in a …

Bariatric and metabolic surgery (BMS) is the most effective treatment for obesity, type 2
diabetes (T2D) and comorbidities, including nonalcoholic fatty liver disease (NAFLD) and …

Insulin resistance is a common feature of obesity and type 2 diabetes, but novel approaches
of diabetes subtyping (clustering) revealed variable degrees of insulin resistance in people …

Background: Women with polycystic ovary syndrome (PCOS) often change their metabolic
profile over time to decrease levels of androgens while often gaining a propensity for the …