Stochasticity in gene body methylation
C Goeldel, F Johannes - Current Opinion in Plant Biology, 2023 - Elsevier
Gene body methylation (gbM) is a widely conserved epigenetic feature of plant genomes.
Efforts to delineate the mechanisms by which gbM contributes to transcriptional regulation …
Efforts to delineate the mechanisms by which gbM contributes to transcriptional regulation …
Epimutations define a fast-ticking molecular clock in plants
N Yao, RJ Schmitz, F Johannes - Trends in Genetics, 2021 - cell.com
Stochastic gains and losses of DNA methylation at CG dinucleotides are a frequent
occurrence in plants. These spontaneous 'epimutations' occur at a rate that is 100 000 times …
occurrence in plants. These spontaneous 'epimutations' occur at a rate that is 100 000 times …
An evolutionary epigenetic clock in plants
Molecular clocks are the basis for dating the divergence between lineages over
macroevolutionary timescales (~ 105 to 108 years). However, classical DNA-based clocks …
macroevolutionary timescales (~ 105 to 108 years). However, classical DNA-based clocks …
Molecular properties of epimutation hotspots
Mistakes in the maintenance of CG methylation are a source of heritable epimutations in
plants. Multigenerational surveys indicate that the rate of these stochastic events varies …
plants. Multigenerational surveys indicate that the rate of these stochastic events varies …
Evolutionary and functional genomics of DNA methylation in maize domestication and improvement
DNA methylation is a ubiquitous chromatin feature, present in 25% of cytosines in the maize
genome, but variation and evolution of the methylation landscape during maize …
genome, but variation and evolution of the methylation landscape during maize …
Millennia-long epigenetic fluctuations generate intragenic DNA methylation variance in Arabidopsis populations
Methylation of CG dinucleotides (mCGs), which regulates eukaryotic genome functions, is
epigenetically propagated by Dnmt1/MET1 methyltransferases. How mCG is established …
epigenetically propagated by Dnmt1/MET1 methyltransferases. How mCG is established …
Heterochromatin is a quantitative trait associated with spontaneous epiallele formation
Epialleles are meiotically heritable variations in expression states that are independent from
changes in DNA sequence. Although they are common in plant genomes, their molecular …
changes in DNA sequence. Although they are common in plant genomes, their molecular …
The unusual predominance of maintenance DNA methylation in Spirodela polyrhiza
Duckweeds are among the fastest reproducing plants, able to clonally divide at exponential
rates. However, the genetic and epigenetic impact of clonality on plant genomes is poorly …
rates. However, the genetic and epigenetic impact of clonality on plant genomes is poorly …
[HTML][HTML] Concepts, mechanisms and implications of long-term epigenetic inheritance
Many modes and mechanisms of epigenetic inheritance have been elucidated in
eukaryotes. Most of them are relatively short-term, generally not exceeding one or a few …
eukaryotes. Most of them are relatively short-term, generally not exceeding one or a few …
Local diversity of drought resistance and resilience in Populus tomentosa correlates with the variation of DNA methylation
J Zhou, L Xiao, R Huang, F Song, L Li… - Plant, Cell & …, 2023 - Wiley Online Library
Little information is known about DNA methylation variation in shaping environment‐specific
drought resistance and resilience for tree adaptation. In this study, we leveraged RNA …
drought resistance and resilience for tree adaptation. In this study, we leveraged RNA …