Therapeutic antibodies (IgG-type) contain several post-translational modifications (PTMs)
whereby introducing a large heterogeneity, both structural and functional, into this class of …

N-glycosylation is one of major post-translational modifications in nature, and it is essential
for protein structure and function. As hydrophilic moieties of glycoproteins, N-glycans play …

The computational prediction of the viscosity of dense protein solutions is highly desirable,
for example, in the early development phase of high-concentration biopharmaceutical …

Monoclonal antibodies (mAbs) are the fastest-growing biological therapeutics with important
applications ranging from cancers, autoimmunity diseases and metabolic disorders to …

The antibody is one of the most well-studied multi-domain proteins because of its
abundance and physiological importance. In this article, we describe the effect of the …

Antibodies of the IgG class carry a pair of oligosaccharides (N-glycans) in the Fc region. The
importance of the N-glycan is clearly demonstrated by its profound effect in the …

Therapeutic monoclonal antibodies and Fc-fusion proteins are successfully used in
treatment of various diseases mainly including cancer, immune disease, and viral infection …

Therapeutic monoclonal antibodies (mAbs) are the fastest growing group of drugs with 11
new antibodies or antibody-drug conjugates approved by the Food and Drug Administration …

This study was undertaken to evaluate the antidiabetic, hypolipidemic, and hepatoprotective
effects of methanol and aqueous extracts of Ganoderma applanatum (MEGA, AEGA) in …

Gynura nepalensis DC (family: Asteraceae) has abundant uses in the alternative medicinal
practice, and this species is commonly used in the treatment of diabetes, rheumatism, cuts or …