The cell, as the most fundamental unit of life, is a microcosm of biology in which the
confluence of nearly all aspects of classical physics (mechanics, statistical physics …

1. Introduction 172. Dynamics of many-body systems 192.1 Effective dynamics of reduced
systems 212.2 The constraint of thermodynamic equilibrium 242.3 Mean-field theories 253 …

Potassium channels play critical roles in many physiological processes, providing a
selective permeation route for K+ ions in and out of a cell, by employing a carefully designed …

How does the brain work? After a century of research, we still lack a coherent view of how
neurons process signals and control our activities. But as the field of computational …

Potassium channels are tetrameric membrane-spanning proteins that provide a selective
pore for the conduction of K+ across the cell membranes. One of the main physiological …

The selectivity filter of potassium channels is the structural element directly responsible for
the selective and rapid conduction of K+, whereas other parts of the protein are thought to …

Potassium channels have been studied intensively in terms of the relationship between
molecular structure and physiological function. They provide an opportunity to integrate …

Ion channels catalyze the permeation of charged molecules across cell membranes and are
essential for many vital physiological functions, including nerve and muscle activity. To …

Narrow hydrophobic regions are a common feature of biological channels, with possible
roles in ion-channel gating. We study the principles that govern ion transport through narrow …

▪ Abstract Potassium (K+) channels are tetrameric membrane-spanning proteins that provide
a selective pore for the conductance of K+ across the cell membranes. These channels are …