Normal haemostasis depends on an intricate balance between mechanisms of bleeding and
mechanisms of thrombosis, and this balance can be altered after traumatic brain injury (TBI) …

The magnitude of damage to cerebral tissues following head trauma is determined by the
primary injury, caused by the kinetic energy delivered at the time of impact, plus numerous …

Traumatic brain injury has long been associated with abnormal coagulation parameters, but
the exact mechanisms underlying this phenomenon are poorly understood. Coagulopathy …

Coagulopathy after traumatic brain injury (TBI) is frequent and represents a powerful
predictor related to outcome and prognosis. The complex pathophysiological mechanisms of …

Persistent intracerebral hemorrhage (ICH) is a major cause of death and disability after
traumatic brain injury (TBI) for which no medical treatment is available. Delayed bleeding is …

Background Severe traumatic brain-injured (TBI) patients should be primarily admitted to a
hub trauma center (hospital with neurosurgical capabilities) to allow immediate delivery of …

Severe traumatic brain injury (sTBI) is a major contributor to long-term disability and a
leading cause of death worldwide. Medical management of the sTBI patient, beginning with …

The focus of this paper is to identify and quantify risk factors for early hemorrhagic
progression of brain contusions (HPC) in patients with traumatic brain injury (TBI) and to …

The increase in the volume of a traumatic intracerebral hemorrhage (TICH) is a widely
studied phenomenon that has a direct impact on the prognosis of patients. The objective of …

Traumatic brain injury (TBI) has long been associated with coagulopathy; however, the time
course of coagulation/fibrinolytic parameters in the acute phase of TBI remains unclear. The …