RNA packaging into extracellular vesicles: An orchestra of RNA‐binding proteins?

F Fabbiano, J Corsi, E Gurrieri… - Journal of …, 2020 - Wiley Online Library
Extracellular vesicles (EVs) are heterogeneous membranous particles released from the
cells through different biogenetic and secretory mechanisms. We now conceive EVs as …

Molecular aspects of cancer cell resistance to chemotherapy

M Rebucci, C Michiels - Biochemical pharmacology, 2013 - Elsevier
Cancer cell resistance to chemotherapy is still a heavy burden that impairs treatment of
cancer patients. Both intrinsic and acquired resistance results from the numerous genetic …

Y-box-binding protein 1 (YB-1) and its functions

IA Eliseeva, ER Kim, SG Guryanov… - Biochemistry …, 2011 - Springer
This review describes the structure and functions of Y-box binding protein 1 (YB-1) and its
homologs. Interactions of YB-1 with DNA, mRNAs, and proteins are considered. Data on the …

A comprehensive review of the functions of YB-1 in cancer stemness, metastasis and drug resistance

A Alkrekshi, W Wang, PS Rana, V Markovic… - Cellular signalling, 2021 - Elsevier
The Y Box binding protein 1 (YB-1) is a member of the highly conserved Cold Shock Domain
protein family with multifunctional properties both in the cytoplasm and inside the nucleus …

YB-1: oncoprotein, prognostic marker and therapeutic target?

A Lasham, CG Print, AG Woolley, SE Dunn… - Biochemical …, 2013 - portlandpress.com
Hanahan and Weinberg have proposed the 'hallmarks of cancer'to cover the biological
changes required for the development and persistence of tumours [Hanahan and Weinberg …

YB-1 is a positive regulator of KLF5 transcription factor in basal-like breast cancer

D Jiang, T Qiu, J Peng, S Li, Tala, W Ren… - Cell Death & …, 2022 - nature.com
Y-box binding protein 1 (YB-1) is a well-known oncogene highly expressed in various
cancers, including basal-like breast cancer (BLBC). Beyond its role as a transcription factor …

Oncogenic Y‐box binding protein‐1 as an effective therapeutic target in drug‐resistant cancer

M Kuwano, T Shibata, K Watari, M Ono - Cancer science, 2019 - Wiley Online Library
Y‐box binding protein‐1 (YBX 1), a multifunctional oncoprotein containing an evolutionarily
conserved cold shock domain, dysregulates a wide range of genes involved in cell …

Y-Box Binding Protein-1 Induces the Expression of CD44 and CD49f Leading to Enhanced Self-Renewal, Mammosphere Growth, and Drug Resistance

K To, A Fotovati, KM Reipas, JH Law, K Hu, J Wang… - Cancer research, 2010 - AACR
Abstract Y-box binding protein-1 (YB-1) is an oncogenic transcription/translation factor
expressed in> 40% of breast cancers, where it is associated with poor prognosis, disease …

Diffusion-weighted imaging in breast cancer: relationship between apparent diffusion coefficient and tumour aggressiveness

M Costantini, P Belli, P Rinaldi, E Bufi, G Giardina… - Clinical radiology, 2010 - Elsevier
AIM: To assess the utility of diffusion-weighted imaging in diagnosing and characterizing
breast malignancy. MATERIALS AND METHODS: From April 2006 to April 2009, all …

Breast cancers: MR imaging of folate-receptor expression with the folate-specific nanoparticle P1133

R Meier, TD Henning, S Boddington, S Tavri, S Arora… - Radiology, 2010 - pubs.rsna.org
Purpose To assess the capability of the folate receptor (FR)-targeted ultrasmall
superparamagnetic iron oxide (USPIO) P1133 to provide FR-specific enhancement of breast …