Polymeric micelles and cancer therapy: An ingenious multimodal tumor-targeted drug delivery system

SK Hari, A Gauba, N Shrivastava, RM Tripathi… - Drug Delivery and …, 2023 - Springer
Since the beginning of pharmaceutical research, drug delivery methods have been an
integral part of it. Polymeric micelles (PMs) have emerged as multifunctional nanoparticles in …

Biomedical application of graphene: From drug delivery, tumor therapy, to theranostics

S Song, H Shen, Y Wang, X Chu, J Xie, N Zhou… - Colloids and Surfaces B …, 2020 - Elsevier
The rise of graphene has driven great revolution in various fields, eg electronics, device,
energy, etc., owing to the well-researched understanding of its physical and chemical …

Anti‐oxidative and anti‐inflammatory micelles: break the dry eye vicious cycle

S Li, Z Lu, Y Huang, Y Wang, Q Jin, X Shentu… - Advanced …, 2022 - Wiley Online Library
Dry eye disease (DED) impacts≈ 30% of the world's population and causes serious ocular
discomfort and even visual impairment. Inflammation is one core cause of the DED vicious …

A Versatile prodrug strategy to in situ encapsulate drugs in MOF nanocarriers: a case of cytarabine‐IR820 prodrug encapsulated ZIF‐8 toward chemo‐photothermal …

H Zhang, Q Li, R Liu, X Zhang, Z Li… - Advanced Functional …, 2018 - Wiley Online Library
Abstract Zeolitic imidazolate framework‐8 (ZIF‐8) is an attractive metal organic framework
(MOF) in drug delivery. Strong interaction between drugs and ZIF‐8 is essential for high drug …

Nitric oxide as an all-rounder for enhanced photodynamic therapy: Hypoxia relief, glutathione depletion and reactive nitrogen species generation

Y Deng, F Jia, S Chen, Z Shen, Q Jin, G Fu, J Ji - Biomaterials, 2018 - Elsevier
A glutathione (GSH)-sensitive supramolecular nitric oxide (NO) nanogenerator is developed
as an all-rounder for enhanced photodynamic therapy (PDT). By integrating GSH-sensitive …

Hyaluronic acid-shelled acid-activatable paclitaxel prodrug micelles effectively target and treat CD44-overexpressing human breast tumor xenografts in vivo

Y Zhong, K Goltsche, L Cheng, F Xie, F Meng, C Deng… - Biomaterials, 2016 - Elsevier
The therapeutic efficacy of nanoscale anticancer drug delivery systems is severely truncated
by their low tumor-targetability and inefficient drug release at the target site. Here, we report …

Tumor-penetrating peptide enhances transcytosis of silicasome-based chemotherapy for pancreatic cancer

X Liu, P Lin, I Perrett, J Lin, YP Liao… - The Journal of …, 2017 - Am Soc Clin Investig
Pancreatic ductal adenocarcinoma (PDAC) is almost uniformly fatal; however, some
improvement in overall survival has been achieved with the introduction of nanocarriers that …

Next generation NIR fluorophores for tumor imaging and fluorescence-guided surgery: A review

A Haque, MSH Faizi, JA Rather, MS Khan - Bioorganic & medicinal …, 2017 - Elsevier
Cancer is a group of diseases responsible for the major causes of mortality and morbidity
among people of all ages. Even though medical sciences have made enormous growth …

Recent progress of graphene oxide-based multifunctional nanomaterials for cancer treatment

L Liu, Q Ma, J Cao, Y Gao, S Han, Y Liang… - Cancer …, 2021 - Springer
Background In the last decade, graphene oxide-based nanomaterials, such as graphene
oxide (GO) and reduced graphene oxide (rGO), have attracted more and more attention in …

Supramolecular aggregation-induced emission nanodots with programmed tumor microenvironment responsiveness for image-guided orthotopic pancreatic cancer …

X Chen, H Gao, Y Deng, Q Jin, J Ji, D Ding - ACS nano, 2020 - ACS Publications
Supramolecular nanomaterials as drug carriers have recently received increasing attention
due to their intrinsic merits such as high stability, strong inclusion capability, and facile …