Doxorubicin—an agent with multiple mechanisms of anticancer activity
Doxorubicin (DOX) constitutes the major constituent of anti-cancer treatment regimens
currently in clinical use. However, the precise mechanisms of DOX's action are not fully …
currently in clinical use. However, the precise mechanisms of DOX's action are not fully …
Mechanisms of chemotherapy-induced neurotoxicity
Since the first clinical trials conducted after World War II, chemotherapeutic drugs have been
extensively used in the clinic as the main cancer treatment either alone or as an adjuvant …
extensively used in the clinic as the main cancer treatment either alone or as an adjuvant …
Toxic effects and molecular mechanism of doxorubicin on different organs–an update
K Renu, LP Pureti, B Vellingiri… - Toxin …, 2022 - Taylor & Francis
Doxorubicin is an extensively used anti-neoplastic drug used for solid and hematogenous
cancer since the 1950s, and its usage is limited due to its toxic effects upon various organs …
cancer since the 1950s, and its usage is limited due to its toxic effects upon various organs …
[HTML][HTML] Comparative evaluation of doxorubicin, cyclophosphamide, 5-fluorouracil, and cisplatin on cognitive dysfunction in rats: Delineating the role of inflammation of …
LI Alotayk, MA Aldubayan, SK Alenezi… - Biomedicine & …, 2023 - Elsevier
Chemotherapeutic agents such as doxorubicin, cyclophosphamide, fluorouracil, and
cisplatin are commonly used to treat a variety of cancers and often result in chemobrain …
cisplatin are commonly used to treat a variety of cancers and often result in chemobrain …
Neuroprotective potential of berberine against doxorubicin-induced toxicity in rat's brain
G Ibrahim Fouad, KA Ahmed - Neurochemical Research, 2021 - Springer
Chemotherapy-associated neurotoxicity is one of the principal side-effects for doxorubicin
(DOX)-treated cancer patients. Despite its poor-penetration across the blood–brain barrier …
(DOX)-treated cancer patients. Despite its poor-penetration across the blood–brain barrier …
Berberine ameliorates doxorubicin-induced cognitive impairment (chemobrain) in rats
FH Shaker, MO El-Derany, SA Wahdan… - Life sciences, 2021 - Elsevier
Aims Cognitive decline is one of the most challenging issues for cancer survivors
undergoing doxorubicin (DOX) based chemotherapy. Oxidative stress and inflammation …
undergoing doxorubicin (DOX) based chemotherapy. Oxidative stress and inflammation …
Role of inflammation and oxidative stress in chemotherapy-induced neurotoxicity
Chemotherapeutic agents may adversely affect the nervous system, including the neural
precursor cells as well as the white matter. Although the mechanisms are not completely …
precursor cells as well as the white matter. Although the mechanisms are not completely …
A review on the neurotoxic effects of doxorubicin
K Kamińska, A Cudnoch-Jędrzejewska - Neurotoxicity Research, 2023 - Springer
Anthracyclines, a class of drugs considered as most effective anticancer drugs, used in the
various regimens of cancer chemotherapy, induce long-term impairment of mitochondrial …
various regimens of cancer chemotherapy, induce long-term impairment of mitochondrial …
Role of flavonoids against adriamycin toxicity
MD Navarro-Hortal, A Varela-López… - Food and Chemical …, 2020 - Elsevier
Abstract Doxorubicin (DOX), or adriamycin, is an anthracycline antineoplastic drug widely
used in the chemotherapy of a large variety of cancers due to its potency and action …
used in the chemotherapy of a large variety of cancers due to its potency and action …
Nanotechnology Approaches for Prevention and Treatment of Chemotherapy‐Induced Neurotoxicity, Neuropathy, and Cardiomyopathy in Breast and Ovarian Cancer …
S Nevins, CD McLoughlin, A Oliveros, JB Stein… - Small, 2023 - Wiley Online Library
Nanotechnology has emerged as a promising approach for the targeted delivery of
therapeutic agents while improving their efficacy and safety. As a result, nanomaterial …
therapeutic agents while improving their efficacy and safety. As a result, nanomaterial …