Primary open-angle glaucoma (POAG) is a leading cause of blindness worldwide. To
identify new susceptibility loci, we performed meta-analysis on genome-wide association …

Despite its tremendous complexity, the vertebrate nervous system emerges from a
homogenous layer of neuroepithelial cells, the neural plate. Its formation relies on the time …

Since its first discovery in the late 90s, Wnt canonical signaling has been demonstrated to
affect a large variety of neural developmental processes, including, but not limited to …

Transcriptional networks defining stemness in adult neural stem cells (NSC s) are largely
unknown. We used the proximal cis‐regulatory element (pCRE) of the retina‐specific …

The troglomorphic phenotype shared by diverse cave-dwelling animals is regarded as a
classical example of convergent evolution. One unresolved question is whether the …

The development of an organism is orchestrated by the spatial and temporal expression of
genes. Accurate visualisation of gene expression patterns in the context of the surrounding …

Within the developing vertebrate retina, particular subtypes of amacrine cells (ACs) tend to
arise from progenitors expressing the basic helix-loop-helix (bHLH) transcription factor …

Divisions that generate one neuronal lineage-committed and one self-renewing cell
maintain the balance of proliferation and differentiation for the generation of neuronal …

Abstract Development requires the implementation of a plethora of molecular mechanisms,
involving a large set of genes to ensure proper cell differentiation, morphogenesis of tissues …

Recent studies revealed new insights into the development of a unique caudal forebrain-
signaling center: the zona limitans intrathalamica (zli). The zli is the last brain signaling …