Recent applications of immunomodulatory biomaterials for disease immunotherapy

H Dai, Q Fan, C Wang - Exploration, 2022 - Wiley Online Library
Immunotherapy is used to regulate systemic hyperactivation or hypoactivation to treat
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …

Plant‐derived extracellular vesicles: recent advancements and current challenges on their use for biomedical applications

MQ Lian, WH Chng, J Liang, HQ Yeo… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) represent a diverse class of lipid bilayer membrane vesicles
released by both animal and plant cells. These ubiquitous vesicles are involved in …

Advanced biomaterials for regulating polarization of macrophages in wound healing

J Mao, L Chen, Z Cai, S Qian, Z Liu… - Advanced Functional …, 2022 - Wiley Online Library
Macrophage immunotherapy is an emerging treatment strategy that modulates the immune
system to promote wound healing. The functionality and regeneration of tissue depend on …

Harnessing polymer-derived drug delivery systems for combating inflammatory bowel disease

Y Pu, X Fan, Z Zhang, Z Guo, Q Pan, W Gao… - Journal of Controlled …, 2023 - Elsevier
The inflammatory bowel disease (IBD) is incurable, chronic, recrudescent disorders in the
inflamed intestines. Current clinic treatments are challenged by systemic exposure-induced …

The emerging role of plant-derived exosomes-like nanoparticles in immune regulation and periodontitis treatment

Z Zhang, Y Yu, G Zhu, L Zeng, S Xu, H Cheng… - Frontiers in …, 2022 - frontiersin.org
Periodontitis is an infectious oral disease, which leads to the destruction of periodontal
tissues and tooth loss. Although the treatment of periodontitis has improved recently, the …

Nanoparticles for oral delivery: targeted therapy for inflammatory bowel disease

D Li, M Yang, H Xu, M Zhu, Y Zhang, C Tian… - Journal of Materials …, 2022 - pubs.rsc.org
As a group of chronic and idiopathic gastrointestinal (GI) disorders, inflammatory bowel
disease (IBD) is characterized by recurrent intestinal mucosal inflammation. Oral …

Polydopamine‐mediated interfacial functionalization of implants for accelerating infected bone repair through light‐activatable antibiosis and carbon monoxide gas …

Z Yuan, J Wu, Z Fu, S Meng, L Dai… - Advanced Functional …, 2022 - Wiley Online Library
Current treatments for implant‐associated infection remain unsatisfactory due to secondary
infection and excessive inflammation, which impairs osseointegration. Herein, an interfacial …

The in vivo fate and targeting engineering of crossover vesicle-based gene delivery system

XC Jiang, T Zhang, JQ Gao - Advanced drug delivery reviews, 2022 - Elsevier
Exosomes and biomimetic vesicles are widely used for gene delivery because of their
excellent gene loading capacity and stability and their natural targeting delivery potential …

Plant-derived exosomes as a drug-delivery approach for the treatment of inflammatory bowel disease and colitis-associated cancer

Y Cai, L Zhang, Y Zhang, R Lu - Pharmaceutics, 2022 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic recurrent intestinal disease and includes
Crohn's disease (CD) and ulcerative colitis (UC). Due to the complex etiology of colitis, the …

Engineering fucoxanthin-loaded probiotics' membrane vesicles for the dietary intervention of colitis

D Liang, C Liu, Y Li, C Wu, Y Chen, M Tan, W Su - Biomaterials, 2023 - Elsevier
Extracellular vesicles (EVs) are very attractive as carriers of active components due to their
good immunological and their ability to penetrate the physiological barrier that synthetic …