A variety of cognitive disorders are worsened by stress exposure and involve dysfunction of
the newly evolved prefrontal cortex (PFC). Exposure to acute, uncontrollable stress …

Autism Spectrum Disorders (ASD) and Schizophrenia (SCZ) are cognitive disorders with
complex genetic architectures but overlapping behavioral phenotypes, which suggests …

Continual learning aims to empower artificial intelligence with strong adaptability to the real
world. For this purpose, a desirable solution should properly balance memory stability with …

Dendritic spines are small protrusions studding neuronal dendrites, first described in 1888
by Ramón y Cajal using his famous Golgi stainings. Around 50 years later the advance of …

Dendritic spines are the major loci of synaptic plasticity and are considered as possible
structural correlates of memory. Nonetheless, systematic manipulation of specific subsets of …

Substantial progress has been made toward understanding the genetic architecture, cellular
substrates, brain circuits and endophenotypic profiles of neuropsychiatric disorders …

The introduction of high-resolution time lapse imaging and molecular biological tools has
changed dramatically the rate of progress towards the understanding of the complex …

Major depressive disorder is associated with abnormalities in the brain and the immune
system. Chronic stress in animals showed that epigenetic and inflammatory mechanisms …

Schizophrenia is a neurodevelopmental disorder whose clinical features include
impairments in perception, cognition and motivation. These impairments reflect alterations in …

Recent studies have provided long-sought evidence that behavioural learning involves
specific synapse gain and elimination processes, which lead to memory traces that influence …