Vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen in vitro and
an angiogenic inducer in a variety of in vivo models. Hypoxia has been shown to be a major …

New blood vessel formation (angiogenesis) is fundamental to tumor growth, invasion, and
metastatic dissemination. The vascular endothelial growth factor (VEGF) signaling pathway …

This 2004 volume in the World Health Organization series on histologic and genetic typing
of human tumors covers tumors of the kidney, urinary system, prostate, testis and …

Inactivation of the von Hippel-Lindau tumor suppressor gene is linked to the development of
hereditary (VHL Disease-associated) and sporadic clear cell carcinoma of the kidney. The …

Role of vascular endothelial growth factor in the regulation of angiogenesis. Compelling
evidence indicates that vascular endothelial growth factor (VEGF) is a fundamental regulator …

Angiogenesis is essential for tumor growth. Vascular endothelial growth factor (VEGF) is the
most potent growth factor of tumor neovasculature, has been shown to be up-regulated in …

Biallelic inactivation of the von Hippel–Lindau tumor suppressor gene (VHL) is linked to the
development of hereditary (VHL-associated) and sporadic clear-cell renal carcinomas as …

Vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen and an
angiogenic inducer as well as a mediator of vascular permeability. The biological effects of …

Purpose To review the biology of renal cell carcinoma (RCC) leading to vascular endothelial
growth factor (VEGF) overexpression and the clinical results of VEGF blockade in metastatic …

Angiogenesis is important in the growth and progression of solid tumours. The main pro-
angiogenic factor, namely vascular endothelial growth factor (VEGF), also known as …