Unveiling potent inhibitors for schistosomiasis through ligand-based drug design, molecular docking, molecular dynamics simulations and pharmacokinetics …
Schistosomiasis is a neglected tropical disease which imposes a considerable and enduring
impact on affected regions, leading to persistent morbidity, hindering child development …
impact on affected regions, leading to persistent morbidity, hindering child development …
Traditional Methods for Treatment and Management of Measles in Northern Nigeria: Medicinal plants and their molecular docking
MD Abdulrahman, SW Hamad - Ethnobotany Research and …, 2022 - eprints.tiu.edu.iq
Background: Measles is one of the major causes of death among young children worldwide.
According to the World Health Organization, measles affects more than 20 million people …
According to the World Health Organization, measles affects more than 20 million people …
Design of more potent quinazoline derivatives as EGFRWT inhibitors for the treatment of NSCLC: a computational approach
Background Lung cancer remains the leading and deadly type of cancer worldwide. It was
estimated to account for about 25% of the 7 million people that died as a result of cancer …
estimated to account for about 25% of the 7 million people that died as a result of cancer …
[HTML][HTML] Structure-based design and activity modeling of novel epidermal growth factor receptor kinase inhibitors; an in silico approach
The development of EGFR kinase inhibitors to treat non-small cell lung cancers is an
important medical necessity due to persistent development of resistance by the mutations. In …
important medical necessity due to persistent development of resistance by the mutations. In …
Modelling PIP4K2A inhibitory activity of 1, 7-naphthyridine analogues using machine learning and molecular docking studies
PIP4K2A is a type II lipid kinase that catalyzed the rate-limiting step of the conversion of
phosphatidylinositol-5-phosphate (PI5P) into phosphatidylinositol 4, 5-bisphosphate (PI4 …
phosphatidylinositol-5-phosphate (PI5P) into phosphatidylinositol 4, 5-bisphosphate (PI4 …
Quantitative structure-activity relationship, molecular docking, drug-likeness, and pharmacokinetic studies of some non-small cell lung cancer therapeutic agents
Background Lung cancer has been reported to be among the leading cancer cases in the
world. It was also reported to have caused a lot of death every year and accounted for about …
world. It was also reported to have caused a lot of death every year and accounted for about …
Molecular docking investigation and pharmacokinetic properties prediction of some anilinopyrimidines analogues as egfr t790m tyrosine kinase inhibitors
The most common and deadly type of lung cancers around the globe was the non-small-cell
lung cancer with approximately 1.5 million cases and a 5-year survival rate of less than 20 …
lung cancer with approximately 1.5 million cases and a 5-year survival rate of less than 20 …
[HTML][HTML] In-silico exploration and structure-based design of Praziquantel derivatives as potential inhibitors of schistosoma mansoni Glutathione S-transferase (SmGST)
SC Jáafaru, A Uzairu, MS Sallau, GI Ndukwe… - Scientific African, 2024 - Elsevier
Schistosomiasis is a chronic parasitic disease with significant public health challenges due
to the limited number of treatment options and increasing levels of drug resistance against …
to the limited number of treatment options and increasing levels of drug resistance against …
[HTML][HTML] In silico analysis of noscapine compounds as anti-tumor agents targeting the tubulin receptor
B Nulamuga, A Uzairu, IT Babalola, MT Ibrahim… - Journal of Taibah …, 2023 - Elsevier
Cancer has been become the most common cause of death globally. Pancreatic cancer has
received significant attention from many medicinal chemists and pharmaceutical companies …
received significant attention from many medicinal chemists and pharmaceutical companies …
Structure-based design of some quinazoline derivatives as epidermal growth factor receptor inhibitors
Background The discovery of epidermal growth factor receptor (EGFR) inhibitors for the
treatment of lung cancer, most especially non-small cell lung cancer (NSCLC), was one of …
treatment of lung cancer, most especially non-small cell lung cancer (NSCLC), was one of …