Extracellular miRNAs: from biomarkers to mediators of physiology and disease
miRNAs can be found in serum and other body fluids and serve as biomarkers for disease.
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …
Altered adipose tissue and adipocyte function in the pathogenesis of metabolic syndrome
Over the past decade, great progress has been made in understanding the complexity of
adipose tissue biology and its role in metabolism. This includes new insights into the …
adipose tissue biology and its role in metabolism. This includes new insights into the …
Differential therapeutic effect of extracellular vesicles derived by bone marrow and adipose mesenchymal stem cells on wound healing of diabetic ulcers and …
Extracellular vesicles (EVs) derived from mesenchymal stem cells isolated from both bone
marrow (BMSCs) and adipose tissue (ADSCs) show potential therapeutic effects. These …
marrow (BMSCs) and adipose tissue (ADSCs) show potential therapeutic effects. These …
Extracellular vesicles in angiogenesis
D Todorova, S Simoncini, R Lacroix, F Sabatier… - Circulation …, 2017 - Am Heart Assoc
During the past decade, extracellular vesicles (EVs), which include apoptotic bodies,
microvesicles, and exosomes, have emerged as important players in cell-to-cell …
microvesicles, and exosomes, have emerged as important players in cell-to-cell …
Tissue-engineered bone immobilized with human adipose stem cells-derived exosomes promotes bone regeneration
W Li, Y Liu, P Zhang, Y Tang, M Zhou… - … applied materials & …, 2018 - ACS Publications
Exosomes, nanoscale extracellular vesicles functioning as cell-to-cell communicators, are
an emerging promising therapeutic in the field of bone tissue engineering. Here, we report …
an emerging promising therapeutic in the field of bone tissue engineering. Here, we report …
Extracellular vesicles for tissue repair and regeneration: Evidence, challenges and opportunities
A Nagelkerke, M Ojansivu, L van der Koog… - Advanced drug delivery …, 2021 - Elsevier
Extracellular vesicles (EVs) are biological nanoparticles naturally secreted by cells, acting
as delivery vehicles for molecular messages. During the last decade, EVs have been …
as delivery vehicles for molecular messages. During the last decade, EVs have been …
Obesity may accelerate the aging process
V Salvestrini, C Sell, A Lorenzini - Frontiers in endocrinology, 2019 - frontiersin.org
Lines of evidence from several studies have shown that increases in life expectancy are now
accompanied by increased disability rate. The expanded lifespan of the aging population …
accompanied by increased disability rate. The expanded lifespan of the aging population …
Exosomes from adipose-derived stem cells: the emerging roles and applications in tissue regeneration of plastic and cosmetic surgery
M Xiong, Q Zhang, W Hu, C Zhao, W Lv, Y Yi… - Frontiers in Cell and …, 2020 - frontiersin.org
Adipose-derived stem cells (ASCs) are an important stem cell type separated from adipose
tissue, with the properties of multilineage differentiation, easy availability, high proliferation …
tissue, with the properties of multilineage differentiation, easy availability, high proliferation …
Bioengineered MSC-derived exosomes in skin wound repair and regeneration
H Zhao, Z Li, Y Wang, K Zhou, H Li, S Bi… - Frontiers in Cell and …, 2023 - frontiersin.org
Refractory skin defects such as pressure ulcers, diabetic ulcers, and vascular ulcers
represent a challenge for clinicians and researchers in many aspects. The treatment …
represent a challenge for clinicians and researchers in many aspects. The treatment …
Mesenchymal stromal cell secretome for the treatment of immune-mediated inflammatory diseases: latest trends in isolation, content optimization and delivery …
Considering the high prevalence and the complex pharmacological management of immune-
mediated inflammatory diseases (IMIDs), the search for new therapeutic approaches for their …
mediated inflammatory diseases (IMIDs), the search for new therapeutic approaches for their …