Chordomas: a review with emphasis on their pathophysiology, pathology, molecular biology, and genetics

G Karpathiou, JM Dumollard, M Dridi, P Dal Col… - … -Research and Practice, 2020 - Elsevier
Chordomas are uncommon, bone, axial, or (rarely) extra-axial tumors that are malignant and
frequently recur but less commonly metastasize. They usually affect adults, with a very small …

Clinicopathological and prognostic characteristics in dedifferentiated/poorly differentiated chordomas: a pooled analysis of individual patient data from 58 studies and …

FS Liu, BW Zheng, TL Zhang, J Li, GH Lv… - Frontiers in …, 2021 - frontiersin.org
Background Currently, the clinicopathological and prognostic characteristics of
dedifferentiated chordoma (DC) and poorly differentiated chordoma (PDC) remain poorly …

Clinicopathological and prognostic characteristics in spinal chondroblastomas: a pooled analysis of individual patient data from a single institute and 27 studies

BW Zheng, W Huang, FS Liu, TL Zhang… - Global Spine …, 2023 - journals.sagepub.com
Study Design: Retrospective pooled analysis of individual patient data. Objectives: Spinal
chondroblastoma (CB) is a very rare pathology and its clinicopathological and prognostic …

[HTML][HTML] A nomogram to predict the progression-free survival of clival chordoma

Y Zhai, J Bai, M Li, S Wang, C Li, X Wei… - Journal of neurosurgery, 2019 - thejns.org
OBJECTIVE Chordoma shows poor patient prognosis because of its high recurrence rate.
Even though many clinical factors and biomarkers are reported to be associated with …

Poorly differentiated extra-axial extraskeletal chordoma diagnosed by methylation profiling: case report and analysis of brachyury expression in SWI/SNF-deficient …

N Klubíčková, M Michal, Z Kinkor, J Soukup, A Ryška… - Virchows Archiv, 2024 - Springer
Chordoma is a rare malignant tumor with notochordal differentiation, usually affecting the
axial skeleton of young patients. We report a case of a high-grade epithelioid tumor …

PALB2 as a factor to predict the prognosis of patients with skull base chordoma

Y Xiong, M Li, Y Shen, T Ma, J Bai, Y Zhang - Frontiers in Oncology, 2022 - frontiersin.org
Objective This study aimed to study the role of PALB2 on the prognosis of skull base
chordoma patients and the proliferation, migration, and invasion of chordoma cells. Methods …

Extraaxial Poorly Differentiated Chordoma: Clinicopathologic and Molecular Genetic Characterization

WJ Sande, AL Folpe, P O'Connor, D Graham… - Modern Pathology, 2025 - Elsevier
Poorly differentiated chordoma (PDC) is an aggressive subtype of chordoma characterized
by SMARCB1 (INI1) loss and a dismal prognosis. It typically involves the axial skeleton, most …

Surgical effects of resecting skull base tumors using pre-operative multimodal image fusion technology: a retrospective study

Z Jian, J Li, K Wu, Y Li, S Li, H Chen, G Chen - Frontiers in Neurology, 2022 - frontiersin.org
Objectives To analyze the surgical effects of resecting skull base tumors using multimodal
three-dimensional (3D) image fusion technology in the neurosurgery department and …

[HTML][HTML] Extra-axial chordoma of the thumb: Report of a rare case with clinicopathologic and molecular analysis

SG Tehrani, NS Kaltoft, LC Melchior, AC Loya - Pathology-Research and …, 2021 - Elsevier
Chordoma is a very rare malignant tumor, with a phenotype that recapitulates notochord,
and is chiefly located in the axial skeleton with only few cases reported in the extra-axial …

Primary extra-axial chondroid chordoma of the anterior nasal septum: case report of a rare chordoma with literature review

C Holley, T Breining, M Scheithauer, P Möller… - HNO, 2021 - Springer
Ein 87-jähriger Patient berichtete über eine knotige, größenprogrediente Struktur des
anterioren Nasenseptums mit partieller Verlegung der Naseneingänge. In der Bildgebung …